摘要
目的分析中青年高血压患者焦虑情绪与血压变异性(BPV)的相关性,提高中青年高血压合并焦虑患者降压的达标率,同时降低高血压相关靶器官损害发生率,改善远期预后。方法选择2020年1月至2021年1月于中国人民解放军总医院心内科住院的中青年高血压患者332例为研究对象,记录患者一般临床数据,并对所有患者进行24 h动态血压监测。根据既往或此次住院期间是否合并焦虑,将研究对象分为高血压合并焦虑组(焦虑组)和单纯性高血压组(观察组),比较两组的一般基线资料、血压水平、BPV,采用多元线性回归分析焦虑与中青年高血压患者BPV的相关性。BPV以血压标准差(SD)表示。结果焦虑组24 h、白天、夜间收缩压(24 hSBP、dSBP、nSBP)及舒张压(24 hDBP、dDBP、nDBP)均高于观察组(P均<0.05);矫正混杂因素后,焦虑与BPV(24 hSBP-SD、dSBP-SD、nSBP-SD、24 hDBP-SD、dDBP-SD)独立相关,(B=3.289,B=2.987,B=1.916,B=1.755,B=1.809,P均<0.05)。结论焦虑会升高中青年原发性高血压患者的BPV。早期识别和积极的心理干预有助于降低高血压合并焦虑患者的BPV,降低高血压相关靶器官损害发病率,改善中青年高血压患者远期预后。
Objective To analyze the correlation anxiety and blood pressure variability(BPV)in young and middle-aged patients with essential hypertension(EH),rise compliance rate of blood pressure(BP),reduce incidence rate of target organ damage related to hypertension,and improve long-term prognosis in young and middle-aged patients with EH complicated anxiety.Methods The young and middle-aged patients with EH(n=332)were chosen as study objects from Department of Cardiology in Chinese PLA General Hospital from Jan.2020 to Jan.2021.The clinical data were recorded and 24 h ambulatory blood pressure monitoring(ABPM)were performed in all patients.The patients were divided,according to whether they had anxiety or not in the past or during this hospitalization,into EH+anxiety group(anxiety group)and EH group(observation group).The baseline materials,BP level and BPV were compared between 2 groups.The correlation between anxiety and BPV was analyzed by using multiple linear regression analysis.BPV was represented by standard deviation(SD)of blood pressure.Results The levels of 24 h systolic BP(24 hSBP),daytime systolic BP(dSBP),nighttime systolic Bp(nSBP),24 h diastolic BP(24 hDBP),daytime diastolic BP(dDBP)and nighttime diastolic BP(nDBP)were all higher in anxiety group than those in observation group(all P<0.05).After correcting confounding factors,anxiety was independently correlated to BPV(24 hSBP-SD:B=3.289,dSBP-SD:B=2.987,nSBP-SD:B=1.916,24 hDBP-SD:B=1.755,dDBP-SD:B=1.809,all P<0.05).Conclusion Anxiety may increase BPV in young and middle-aged patients with EH.Early identification and active psychological intervention can reduce BPV in patients with hypertension complicated by anxiety,decrease the incidence of hypertensive-related target organ damage,and improve long-term prognosis in the young and middle-aged patients with hypertension.
作者
袁梦寒
张瀛月
王晶
刘昱圻
徐勇
Yuan Menghan;Zhang Yingyue;Wang Jing;Liu Yuqi;Xu Yong(Chinese PLA Medical School,Beijing 100853,China;不详)
出处
《中国循证心血管医学杂志》
2023年第1期41-44,共4页
Chinese Journal of Evidence-Based Cardiovascular Medicine
基金
国家重点研发计划(2020YFC2007305)。
关键词
高血压
焦虑
血压变异性
Hypertension
Anxiety
Blood pressure variability
