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手工腹膜透析与自动化腹膜透析机在终末期肾病腹膜透析患者中的应用疗效比较

Comparison of the Efficacy of Manual Peritoneal Dialysis and Automated Peritoneal Dialysis in Patients with End-stage Renal Disease Undergoing Peritoneal Dialysis
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摘要 目的比较手工腹膜透析与自动化腹膜透析机在终末期肾病腹膜透析患者中的应用疗效。方法选取2019年12月-2021年12月于佳木斯市中心医院行腹膜透析治疗的60例终末期肾病患者,按照随机数字表法进行分组,其中手工腹膜透析组(30例),自动化腹膜透析组(30例)。分别应用传统手工腹膜透析与自动化腹膜透析,比较两组矿物质代谢指标[钙(Ca)、磷(P)、全段甲状旁腺激素(iPTH)]、矿物质代谢达标率、肾功能指标[血清尿素氮(BUN)、血清肌酐(Scr)]、并发症情况及随访结局。结果自动化腹膜透析组Ca、P、iPTH指标低于手工腹膜透析组,Ca、P、iPTH代谢达标率高于手工腹膜透析组,Scr、BUN水平低于手工腹膜透析组(P<0.05);自动化腹膜透析组并发症发生率低于对照组(P<0.05);两组继续腹膜透析率、肾移植率、死亡率比较,差异无统计学意义(P>0.05),但自动化腹膜透析组转血液透析率低于手工腹膜透析组(P<0.05)。结论相较于手工腹膜透析,自动化腹膜透析机在终末期肾病透析中的矿物质代谢效果更佳,可缓解肾功能损伤,且并发症少,血液透析中转率较低。 Objective To compare the efficacy of manual peritoneal dialysis and automated peritoneal dialysis machine in peritoneal dialysis patients with end-stage renal disease.Methods From December 2019 to December 2021,60 patients with end-stage renal disease who underwent peritoneal dialysis in Jiamusi Central Hospital were selected and grouped according to the random number table method,including manual peritoneal dialysis group(30 cases)and automated peritoneal dialysis group(30 cases),traditional manual peritoneal dialysis and automated peritoneal dialysis were used respectively.The mineral metabolism indexes[calcium(Ca),phosphorus(P),intact parathyroid hormone(iPTH)],mineral metabolism compliance rate,renal function indexes[blood urea nitrogen(BUN),serum creatinine(Scr)],complications and follow-up outcomes were compared between the two groups.Results The indexes of Ca,P and iPTH in the automated peritoneal dialysis group were lower than those in the manual peritoneal dialysis group,the metabolic compliance rates of Ca,P and iPTH were higher than those in the manual peritoneal dialysis group,and the levels of Scr and BUN were lower than those in the manual peritoneal dialysis group(P<0.05).The incidence of complications in the automated peritoneal dialysis group was lower than that in the control group(P<0.05).There was no significant difference in continuous peritoneal dialysis rate,renal transplantation rate and mortality between the two groups(P>0.05),but the hemodialysis rate in the automated peritoneal dialysis group was lower than that in the manual peritoneal dialysis group(P<0.05).Conclusion Compared with manual peritoneal dialysis,automatic peritoneal dialysis machine has better mineral metabolism effect in end-stage renal disease dialysis,which can alleviate renal function injury,with fewer complications and lower hemodialysis transfer rate.
作者 江雨珊 JIANG Yu-shan(Department of Nephrology,Jiamusi Central Hospital,Jiamusi 154000,Heilongjiang,China)
出处 《医学信息》 2023年第3期136-139,共4页 Journal of Medical Information
关键词 终末期肾病 自动化腹膜透析 手工腹膜透析 矿物质代谢 肾功能 End-stage renal disease Automated peritoneal dialysis Manual peritoneal dialysis Mineral metabolism Renal function
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