摘要
目的:回顾性分析骨痹通消颗粒治疗早中期非创伤性股骨头坏死的临床疗效及安全性。方法:选取2020年1月至2020年12月收治的早中期非创伤性股骨头坏死患者38例,使用骨痹通消颗粒进行治疗,分别于治疗前、治疗后3个月和治疗后1年评估患者的视觉模拟量表(VAS)疼痛评分、Harris髋关节评分、X线片评分及安全性。结果:所有患者治疗期间未出现严重不良反应。治疗3个月及治疗1年时患者VAS疼痛评分较治疗前明显降低,差异有统计学意义(P<0.05)。治疗3个月及治疗1年时Harris评分较治疗前持续改善,差异有统计学意义(P<0.05)。对比治疗1年和治疗前的双髋关节正位片、蛙位片差异无统计学意义(P>0.05)。结论:使用骨痹通消颗粒治疗早中期非创伤性股骨头坏死临床疗效可靠,具有较高的安全性。
Objective:To analyze the clinical efficacy and safety of Gubi Tongxiao granules on the treatment of early and middle stage non-traumatic osteonecrosis of femoral head. Methods:38 cases of patients with early and middle stage non-traumatic femoral head necrosis from January 2020 to December 2020 were selected and treated with Gubi Tongxiao granules.Visual analogue scale(VAS) pain score, Harris hip score, radiographic X-ray score and safety of patients were evaluated before treatment, 3 months, and 1 year after treatment. Results:No serious adverse reactions occurred in all patients during treatment. After 3 months of treatment and 1 year of treatment, the VAS pain scores of the patients were significantly lower than those before treatment, and the difference were statistically significant(P<0.05). The Harris score continued to improve after 3 months of treatment and 1 year after treatment, and the difference was statistically significant(P<0.05). There was no significant difference in the anteroposterior radiographs and frog radiographs of both hips after 1 year of treatment and before treatment, so the difference was not statistically significant(P>0.05). Conclusion:The use of Gubi Tongxiao granules on the treatment of early and middle stage non-traumatic femoral head necrosis has reliable clinical efficacy and higher safety.
作者
侯文渊
朱磊
顾一帆
朱彩玉
周正新
HOU Wenyuan;ZHU Lei;GU Yifan;ZHU Caiyu;ZHOU Zhengxin(Anhui University of Chinese Medicine,Hefei 230031,China;The First Affiliated Hospital of Anhui University of Chinese Medicine,Hefei 230031,China)
出处
《中国中医骨伤科杂志》
CAS
2023年第1期56-60,共5页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
基金
安徽省自然科学基金面上项目(2008085MH281)。
关键词
非创伤性股骨头坏死
早中期
骨痹通消颗粒
回顾性研究
non-traumatic femoral head necrosis
Gubi Tongxiao granules
early and middle stage
retrospective study
