摘要
目的分析心脏瓣膜置换术治疗大左心室心脏瓣膜病的临床疗效。方法抽取2020年1月至2022年1月驻马店市中心医院收治的80例大左心室心脏瓣膜病患者为研究对象,参照计算机分组法将其分为对照组与研究组,每组40例。对照组采用机械瓣膜置换术治疗,研究组采用生物瓣膜置换术治疗。比较两组手术相关指标、心功能指标、并发症发生率、肺功能指标及治疗总有效率。结果研究组手术时间、重症监护病房住院时间、气管插管时间均短于对照组(P均<0.05)。术后,两组心功能指标均优于术前(P均<0.05),但两组间比较差异未见统计学意义(P>0.05)。对照组并发症发生率(27.50%,11/40)高于研究组(10.00%,4/40),P<0.05。术后,两组肺功能指标优于术前,且研究组优于对照组(P<0.05)。研究组治疗总有效率(95.00%,38/40)高于对照组(77.50%,31/40),差异有统计学意义(P<0.05)。结论相较于机械瓣膜置换术,生物瓣膜置换术治疗大左心室心脏瓣膜病的疗效较好,且安全性较高。
Objective To compare the clinical effect of mechanical vale replacement and biological valve replacement in the treatment of large left ventricular valve disease.Methods A total of 80 patients with large left ventricular valve heart disease treated in Zhumadian Central Hospital from January 2020 to January 2022 were selected as the observation objects,and they were divided into the control group and the study group according to the computer grouping method,with 40 cases in each group.The control group was treated by mechanical valve replacement,and the study group was treated by biological valve replacement.The operation related indicators,cardiac function indexes,incidence of complication,lung function indexes and total effective rate were compared between the two groups.Results The operation time,duration of intensive care unit,and tracheal intubation time in the study group were shorter than those in the control group(all P<0.05).After treatment,the cardiac function indexes in the two groups were superior to these indexes before treatment(all P<0.05),however,there was no significant difference between the two groups(P>0.05).The incidence of complications of the control group(27.50%,11/40)was higher than that of the study group(10.00%,4/40),P<0.05.After treatment,the lung function indexes of the two groups were superior to preoperative indexes,and these indexes in the study groups were superior to those in the control group(P<0.05).The total effective rate of the study group(95.00%,38/40)was higher than that of the control group(77.50%,31/40),and the difference was significant(P<0.05).Conclusions Compared with mechanical valve replacement,biological valve replacement has better curative effects and higher safety in the treatment of large left ventricular heart valve disease.
作者
梅永成
浮志坤
潘君晖
余森
李海燕
Mei Yongcheng;Fu Zhikun;Pan Junhui;Yu Sen;Li Haiyan(Department of Cardiac Surgery,Zhumadian Central Hospital,Zhumadian 463000,China;Department of Cardiac Surgery,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)
出处
《中国实用医刊》
2022年第21期6-9,共4页
Chinese Journal of Practical Medicine
基金
河南省医学科技攻关计划项目(2018020861)。
关键词
心脏瓣膜置换术
大左心室心脏瓣膜病
机械瓣膜置换术
生物瓣膜置换术
Heart valve replacement
Large left ventricular valve disease
Mechanical valve replacement
Biological valve replacement
