摘要
为研究植物甾烷醇酯的粉体制备工艺,满足药品及功能食品的开发,通过单因素试验考察料水比、二氧化硅比例、酪蛋白酸钠比例、麦芽糊精比例和进风温度这5个因素对植物甾烷醇酯的粉体制备效果的影响,并通过Plackett-Burman试验考察影响因素的显著性,最后通过Box-Behnken试验对3个显著因素进行响应面优化分析。优化后的喷粉工艺最佳条件为:料水比51.30%,二氧化硅比例4.05%,麦芽糊精比例15.02%。在该条件下制备植物甾烷醇酯粉末,粉末得率为87.04%、粉末中甾醇含量为64.12%,与模型预测值(粉末得率87.281%,粉末中甾醇含量64.1525%)吻合度较高。所制成的植物甾烷醇酯粉末得率及甾醇含量较高,可用于功能食品或药品。
Investigating the preparation process of plant stanol ester power to meet the development of medicines and functional foods. On the basis of single factor experiment,the effects of five factors(solid-liquid ratio,silica ratio,casein sodium ratio,maltodextrin ratio and inlet air temperature of fluidized bed)on preparation process of plant stanol ester power were investigated. Then,the significance of five factors was investigated by Plackett-Burman experiment. Finally,three significant factors(solid-liquid ratio,silica ratio and maltodextrin ratio)were optimized by Box-Behnken experiment. The optimal conditions of the powder spraying process were :solid-liquid ratio was 51.30%,the silica ratio was 4.05%,and the maltodextrin ratio was 15.02%. Under this condition,the yield of plant stanol ester power was 87.04%,the sterol content in the power was 64.12%,which had a high coincidence with the predicted value of the model(87.281% yield of plant stanol ester power,and 64.1525% sterol content in the power).The plant stanol ester power had good fluidity and low moisture absorption,and can be used in functional foods and medicines.
作者
杨善岩
钟建荣
王海东
冯锋将
YANG Shanyan;ZHONG Jianrong;WANG Haidong;FENG Fengjiang(Hangzhou Minsheng Healthcare Pharmaceutical Co.,Ltd.,Hangzhou 311100)
出处
《中国食品添加剂》
CAS
北大核心
2023年第2期121-129,共9页
China Food Additives
关键词
植物甾烷醇酯
喷雾干燥
显著因素
响应面优化
得率
plant stanol ester
spray drying
significant factors
response surface optimization
yield
