摘要
目的:观察活血通络开窍汤联合重复经颅磁刺激(rTMS)治疗脑卒中后认知功能障碍的临床疗效。方法:选取脑卒中后认知功能障碍患者80例,按随机数字表法分为观察组和对照组各40例。对照组给予rTMS治疗,观察组在对照组基础上加活血通络开窍汤治疗,2组均治疗12周。评价2组临床疗效,比较2组治疗前后简易精神状况检查量表(MMSE)评分及改良Barthel指数(MBI)评分。结果:观察组总有效率为95.00%,高于对照组80.00%,差异有统计学意义(P<0.05)。治疗前,2组MMSE评分、MBI评分比较,差异无统计学意义(P>0.05)。治疗后,2组MMSE评分、MBI评分较治疗前升高(P<0.05),且观察组MMSE评分、MBI评分高于对照组(P<0.05)。结论:活血通络开窍汤联合rTMS治疗脑卒中后认知功能障碍的疗效确切,能明显改善患者认知功能,提高日常生活能力。
Objective:To observe the clinical effect of Huoxue Tongluo Kaiqiao Tang combined with repetitive transcranial magnetic stimulation(rTMS) for post-stroke cognitive impairment.Methods:A total of 80 cases of patients with post-stroke cognitive impairment were selected and divided into the observation group and the control group according to the random number table method,with 40 cases in each group.The control group was treated with rTMS,and the observation group was additionally treated with Huoxue Tongluo Kaiqiao Tang based on the treatment of the control group.Both groups were treated for 12 weeks.The clinical effects in the two groups were evaluated.Before and after treatment,the scores of Mini-Mental State Examination(MMSE) and Modified Barthel Index(MBI) in the two groups were compared.Results:The total effective rate was 95.00% in the observation group,higher than that of80.00% in the control group,the difference being significant(P0.05).After treatment,the scores of MMSE and MBI in the two groups were increased when compared with those before treatment(P<0.05),and the scores of MMSE and MBI in the observation group were higher than those in the control group(P<0.05).Conclusion:Huoxue Tongluo Kaiqiao Tang combined with rTMS has a definite curative effect in treating post-stroke cognitive impairment,and can significantly improve cognitive function and activity of daily living.
作者
史海燕
王兆蒙
张超
李征
应松铁
SHI Haiyan;WANG Zhaomeng;ZHANG Chao;LI Zheng;YING Songtie
出处
《新中医》
CAS
2022年第23期65-68,共4页
New Chinese Medicine
基金
宁波市公益科技项目(202002N3170)。
关键词
脑卒中后认知功能障碍
重复经颅磁刺激
活血通络开窍汤
认知功能
日常生活能力
Post-stroke cognitive impairment
Repetitive transcranial magnetic stimulation
Huoxue Tongluo Kaiqiao Tang
Cognitive function
Activity of daily living
