摘要
目的探究西替利嗪对小儿急性上呼吸道感染诱发喘息性支气管炎的预防效果。方法此研究以随机法抽选2017年10月-2020年10月收治的216例急性上呼吸道感染确诊者展开临床观察,以药物干预模式选择的不同,对患儿进行数字编号后行分组,编号1~108者纳为对照组,以常规药物进行干预,编号109~216者纳为研究组,在常规药物的基础上加用西替利嗪。以统计学比较组间观察指标,即组间临床症状的消失时间,治疗前后的炎性指标水平,以及治疗期间喘息、支气管炎、支气管肺炎的出现情况,以评价预防效果。结果研究组患儿的咳嗽、气喘等症状消失时间短于对照组患儿,组间比较有明显统计学差异(P<0.05);治疗前组间WBC、CRP无差异性(P>0.05),治疗后两组均获得改善,且研究组改善更明显(P<0.05);对照组患儿在治疗期间,喘息、支气管炎、支气管肺炎的发生率分别为20.37%、60.19%、22.22%,研究组患儿在治疗期间,喘息、支气管炎、支气管肺炎的发生率分别为9.26%、35.19%、9.26%。治疗期间,研究组患儿出现喘息、支气管炎、支气管肺炎的概率均低于对照组患儿,组间比较有明显统计学差异(P<0.05)。结论对于急性上呼吸道患儿来说,西替利嗪的使用不仅可以改善患儿症状,促进患儿康复,还可有效预防患儿出现喘息性支气管炎,因此,临床应用及推广价值高。
Objective To investigate preventive effect of cetirizine on children with asthmatic bronchitis induced by acute upper respiratory tract infection.Methods The paper chose 216 patients with acute upper respiratory tract infection diagnosed from October 2017 to October 2020 for clinical observation,and divided them into groups after numerical numbering according to different drug intervention modes.Patients numbered 1 to 108 were includied in control group,Intervened with routine drugs,and those numbered 109 to 216 in study group,with cetirizine on the basis of routine drugs.Observation indicators between groups were compared,including disappearance time of clinical symptoms between groups,level of inflammatory indicators before and after treatment,occurrence of wheezing,bronchitis,and bronchopneumonia during treatment,to evaluate prevention effect.Results Disappearance time of cough,asthma and other symptoms of study group was shorter than control group,there was significant statistical difference between the groups(P<0.05);there was no difference in WBC and CRP between two groups before treatment(P>0.05),but both groups improved after treatment,improvement in study group was more obvious(P<0.05).During treatment,incidence of wheezing,bronchitis and bronchopneumonia in control group was 20.37%,60.19%and 22.22%respectively.During treatment,incidence of wheezing,bronchitis and bronchopneumonia in study group was 9.26%,35.19%and 9.26%respectively.During treatment,children in study group had lower incidence of wheezing,bronchitis and bronchopneumonia than control group,with significant statistical difference between the groups(P<0.05).Conclusion Cetirizine can improve symptoms of children with acute upper respiratory tract,promote their rehabilitation,and prevent children from asthmatic bronchitis effectively,which has high clinical application and promotion value.
作者
李云凤
LI Yunfeng(Pediatrics Department,Lanzhou City the Second People's Hospital,Lanzhou,Gansu,730046)
出处
《智慧健康》
2022年第33期67-71,共5页
Smart Healthcare
关键词
西替利嗪
小儿急性上呼吸道感染
喘息性支气管炎
预防效果
Cetirizine
Acute upper respiratory tract infection of children
Asthmatic bronchitis
Preventive effect
