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大肠癌复发转移影响因素的Logistic回归分析

Logistic analysis of influencing factors of recurrence and metastasis of colorectal cancer
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摘要 [目的]对大肠癌复发转移的影响因素进行Logistic分析研究。[方法]入选大肠癌患者370例,将复发转移者列为研究组(190例)、未复发转移者列为对照组(180例),分析比较2组性别、年龄、肿瘤大小和位置、淋巴结转移、Duker’s分期、分化类型等资料。[结果]研究组与对照组在性别、年龄比较,差异无统计学意义(P>0.05),肿瘤大小及位置、淋巴结转移、Duker’s分期、分化程度比较差异有统计学意义(P<0.05)。将以上有统计学差异的因素放入多因素Logistic分析得出,肿瘤位置、肿瘤大小、淋巴结转移、Duker’s分期为导致大肠癌复发转移的危险因素。[结论]肿瘤位置、肿瘤大小、淋巴结转移、Duker’s分期确认为大肠癌复发危险性因素,临床上应针对有此特征的患者加强复查及随访。 [Objective]To study the Logistic analysis of the influencing factors of recurrence and metastasis of colorectal cancer in 190 cases.[Methods]A total of 370 patients with colorectal cancer were enrolled.190 patients with recurrence and metastasis were included in the study group, and 180 patients without recurrence and metastasis were included in the control group.Gender, age, tumor size and location, lymph node metastasis, Duker’s stage, differentiation type and other data were analyzed and compared between the two groups.[Results]There were no statistically significant differences in colorectal cancer recurrence and metastasis in terms of gender and age(P>0.05).There were statistically significant differences in tumor size and location, lymph node metastasis, Duker’s stage and degree of differentiation(P<0.05).The factors with statistical differences above were put into multivariate Logistic analysis, and it was concluded that some factors were risk factors for recurrence and metastasis of such cancers.These factors were tumor location, tumor size, lymph node metastasis and Duker’s stage.[Conclusion]Tumor location, tumor size, lymph node metastasis and Duker’s stage have all been confirmed as factors with high recurrence risk of colorectal cancer, and clinical review and follow-up should be strengthened for patients with such characteristics.
作者 陆园园 殷婷 LU Yuan-yuan;YIN Ting(Department of Oncology,Jiangsu Subei People's Hospital,225001 Yangzhou,Jiangsu,China)
出处 《临床消化病杂志》 CAS 2022年第6期454-456,共3页 Chinese Journal of Clinical Gastroenterology
关键词 大肠癌 复发转移 影响因素 colorectal cancer recurrence and metastasis factors affecting the
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