摘要
目的:观察妇炎汤保留灌肠联合公英败酱汤治疗湿热瘀结型急性子宫内膜炎的临床疗效。方法:将60例急性子宫内膜炎湿热瘀结证患者,按照随机数字表法分为治疗组和对照组,每组30例。治疗组给予妇炎汤保留灌肠联合公英败酱汤口服治疗,对照组给予公英败酱汤口服治疗。观察两组患者治疗前后血清炎症因子水平和子宫内膜厚度变化情况,以及有效率、半年内复发率和不良反应等。结果:治疗组有效率为93.33%,对照组有效率为73.33%,治疗组有效率高于对照组,差异有统计学意义(P<0.05)。治疗组治疗后白细胞介素(interleukin, IL)-2水平高于对照组,IL-6、IL-8、肿瘤坏死因子(tumor necrosis factor, TNF)-α及C反应蛋白(C reactive protein, CRP)水平低于对照组,差异具有统计学意义(P<0.05)。治疗组下腹疼痛缓解时间、白带增多缓解时间以阴道出血缓解时间短于对照组,差异有统计学意义(P<0.05)。治疗组不良反应发生率为20.00%,对照组不良反应发生率为13.33%,两组不良反应发生率比较,差异无统计学意义(P>0.05)。治疗后随访半年,治疗组有1例患者复发,复发率为3.33%,对照组有6例患者复发,复发率为20.00%,治疗组复发率低于对照组,差异有统计学意义(P<0.05)。结论:妇炎汤保留灌肠联合公英败酱汤治疗湿热瘀结型急性子宫内膜炎,能增加患者子宫内膜厚度,促进其修复,其作用机制可能与有效降低血清炎症因子有关。
Objective: To observe the clinical efficacy of Female Inflammation Decoction for Retention Enema combined with Herba Taraxaci and Herba Patriniae Decoction on acute endometritis with dampness-heat stasis syndrome.Methods: A total of 60 patients with acute endometritis with dampness-heat stasis syndrome were randomly divided into the treatment group and the control group, with 30 cases in each group.The treatment group was given Female Inflammation Decoction for Retention Enema combined with Herba Taraxaci and Herba Patriniae Decoction, while the control group was given Herba Taraxaci and Herba Patriniae Decoction for oral treatment.The changes of serum inflammatory factors and endometrial thickness, as well as the effective rate, recurrence rate within half a year and adverse reactions were observed before and after treatment.Results: The effective rate of the treatment group was 93.33%,and that of the control group was 73.33%.The effective rate of the treatment group was higher than that of the control group, with a statistically significant difference(P<0.05).After treatment, the level of IL-2 in the treatment group was higher than that in the control group, while IL-6,IL-8,CRP and TNF-α in the treatment group were higher than those in the control group, with statistically significant differences(P<0.05).The relieving time of lower abdominal pain, leucorrhea increase and vaginal bleeding in the treatment group was shorter than that in the control group, with statistically significant differences(P<0.05).The incidence of adverse reactions in the treatment group was 20.00%,while that in the control group was 13.33%.There was no significant difference between the two groups(P>0.05) After six months of follow-up after treatment, one patient in the treatment group relapsed, with a recurrence rate of 3.33%,and 6 patients in the control group relapsed, with a recurrence rate of 20.00%.The recurrence rate in the treatment group was lower than that in the control group, with a statistically significant difference(P<0.05).Conclusion: Female Inflammation Decoction for Retention Enema combined with Herba Taraxaci and Herba Patriniae Decoction can increase the thickness of endometrium and promote its repair in patients with acute endometritis of dampness-heat stasis type.Its mechanism may be related to its ability to effectively reduce serum inflammatory factors.
作者
彭彩荷
徐倩
余婷
PENG Cai-he;XU Qian;YU Ting(Wannian County Hospital of Traditional Chinese Medicine,Wannian,Jiangxi,China,335500)
出处
《河南中医》
2023年第1期77-81,共5页
Henan Traditional Chinese Medicine
基金
江西省医学科研项目(2021CZDX123)。
关键词
急性子宫内膜炎
湿热瘀结证
妇炎汤
保留灌肠
公英败酱汤
acute endometritis
dampness-heat stasis syndrome
Female Inflammation Decoction
Retention Enema
Herba Taraxaci and Herba Patriniae Decoction
