摘要
目的:探讨ICU气管切开患者呼吸道鲍曼不动杆菌感染的危险因素及耐药性。方法:选取2019年1月-2022年3月在萍乡市人民医院经ICU气管切开患者92例作为研究对象,根据患者是否发生呼吸道鲍曼不动杆菌感染感染分为感染组27例和未感染组65例,分析ICU气管切开患者呼吸道鲍曼不动杆菌的耐药性,并通过多元线性回归分析其独立影响因素。结果:单因素分析结果显示,两组是否感染前联合使用碳青霉烯类抗生素、机械通气时间、白蛋白水平、有无肺部疾病史比较,差异均有统计学意义(P<0.05)。多因素分析结果显示,感染前联合使用碳青霉烯类抗生素、机械通气时间>7 d、白蛋白水平<35 g/L以及有肺部疾病史是ICU气管切开患者呼吸道鲍氏不动杆菌感染的独立影响因素(P<0.05)。耐药分析结果显示,27例呼吸道鲍氏曼不动杆菌感染患者对头孢曲松的耐药达到96.29%,对多种抗生素的耐药≥50%。结论:感染前联合使用碳青霉烯类抗生素、机械通气时间>7 d、白蛋白水平<35 g/L以及有肺部疾病史是ICU气管切开患者呼吸道鲍曼不动杆菌感染的独立影响因素,鲍曼不动杆菌对多种抗菌药物的耐药较高。
Objective:To investigate the risk factors and drug resistance of respiratory Acinetobacter baumannii infection in patients with tracheotomy in ICU.Method:A total of 92 patients with tracheotomy in the ICU of Pingxiang People’s Hospital from January 2019 to March 2022 were selected as the research subjects.According to whether the patients had respiratory tract Acinetobacter baumannii infection or not,they were divided into infection group of 27 cases and non-infection group of 65 cases.The drug resistance of respiratory Acinetobacter baumannii in patients with tracheotomy in ICU was analyzed,and its independent influencing factors were analyzed by multiple linear regression.Result:Univariate analysis showed that there were statistically significant differences between the two groups in whether combined use of carbapenem antibiotics before infection,mechanical ventilation time,albumin level and history of pulmonary disease(P<0.05).Multivariate analysis showed that combined use of carbapenems antibiotics before infection,mechanical ventilation time>7 days,albumin level<35 g/L and history of lung disease were independent influencing factors for respiratory Acinetobacter baumannii infection in ICU patients with tracheotomy(P<0.05).The results of drug resistance analysis showed that the resistance to Ceftriaxone reached 96.29%in 27 patients with respiratory Acinetobacter baumannii infection,and the resistance to multiple antibiotics was more than 50%.Conclusion:Combined use of carbapenems antibiotics before infection,mechanical ventilation time>7 days,albumin level<35 g/L and history of lung disease are independent influencing factors for respiratory Acinetobacter baumannii infection in ICU patients with tracheotomy.Acinetobacter baumannii has high resistance to a variety of antibiotics.
作者
漆柳
QI Liu(Pingxiang People's Hospital,Jiangxi Province,Pingxiang 337055,China)
出处
《中国医学创新》
CAS
2023年第1期156-159,共4页
Medical Innovation of China
关键词
ICU
气管切开
呼吸道
鲍曼不动杆菌
危险因素
耐药情况
ICU
Tracheostomy
Respiratory tract
Acinetobacter baumannii
Risk factors
Drug resistance
