摘要
重症急性胰腺炎(SAP)通常合并以心脏、肾脏功能障碍多见的多器官功能障碍和严重感染,连续性肾脏替代治疗(CRRT)和药物抗感染治疗可能同时进行。本文主要阐述1例SAP合并急性肾损伤(AKI)患者采用CRRT治疗期间使用美罗培南2 g,q.8 h.给药抗感染治疗,获得良好的治疗效果且未发生有关药物不良反应。临床药师通过查找文献证据,充分发挥临床药学专业优势,积极投身临床药物治疗与监护,结合患者肌酐清除率(Ccr)及病情制定药物抗感染治疗方案,使患者得到有效的抗菌药物治疗。保障了患者安全、有效用药,助推临床合理用药,体现了临床药师的价值。
Severe acute pancreatitis(SAP)is usually associated with multiple organ dysfunction that is common in heart and kidney and severe infection.Continuous renal replacement therapy(CRRT)and drug antiinfective therapy may be performed simultaneously.This paper mainly describes a patient with SAP complicated with acute kidney injury(AKI)who received anti-infective therapy with meropenem 2 g,q.8 h.during CRRT treatment,and has achieved good therapeutic effect without adverse drug reactions.By searching for literature evidence,clinical pharmacists give full play to the professional advantages of clinical pharmacy,actively participate in clinical drug treatment and monitoring,and formulate drug anti-infection treatment programs in combination with patients’creatinine clearance rate(Ccr)and disease conditions,so that the patient gets effective antibacterial therapy.It ensures the safe and effective medication of patients,boosts clinical rational drug use,and embodies the value of clinical pharmacists.
作者
胡叶敏
罗浩
杨戈
刘凯
HU Ye-min;LUO Hao;YANG Ge(Luzhou Maternal and Child Health Hospital(Luzhou Second People's Hospital),LuZhou 646000,China)
出处
《中国实用医药》
2022年第26期154-157,共4页
China Practical Medicine
关键词
临床药师
美罗培南
剂量调整
病例分析
合理用药
Clinical pharmacists
Meropenem
Dosage adjustment
Case analysis
Rational medication
