摘要
目的:探究经尿道精囊镜技术(TSV)治疗顽固性血精症(HSS)患者的效果。方法:将86例顽固性HSS患者随机分为对照组和观察组,每组43例。对照组采用超声引导下精囊穿刺置管术治疗,观察组采用TSV治疗。观察并分析两组临床疗效、精子质量、精浆生化指标、搏起功能(IIEF-5评分)、射精功能(CIPE评分)及并发症发生情况。结果:观察组治疗总有效率95.35%高于对照组79.07%,差异有统计学意义(P<0.05);治疗后,观察组精液量、精子密度、A级+B级精子活力占比、精浆果糖(Fru)、α-糖苷酶(α-Glu)、弹性糖蛋白(EA)水平均高于对照组;畸形精子占比、精浆丙二醛(MDA)均低于对照组(P<0.05);观察组IIEF-5、CIPE评分均高于对照组(P<0.05);两组并发症总发生率比较,差异无统计学意义(P>0.05)。结论:TSV治疗顽固性HSS的效果优于超声引导下精囊穿刺置管术治疗,能有效提高精子质量,促进性功能恢复。
Objective: To discuss the effect of transurethral seminal vesiculoscopy(TSV) on patients with refractory hemospermia syndrome(HSS). Methods: 86 cases of refractory HSS patients were randomized into the control group and observation group, each with 43 cases. The control group were treated with ultrasound-guided seminal vesicle puncture and catheterization, while the observation group were treated with TSV. The clinical efficacy, sperm quality, seminal plasma biochemical indicator, erectile function(IIEF-5 score), ejaculation function(CIPE score), and complications were compared between patients in both groups. Results: The total effective rate of the observation group was 95.35%, higher than 79.07% of the control group, and the differences were statistically significant(P<0.05);After treatment, the semen volume, sperm density, the proportion of grade A+B sperm motility, and levels of seminal fructose(Fru), α-glycosylase(α-Glu) and elastic glycoprotein(EA) in the observation group were higher than those in the control group;the proportion of deformed sperm and malondialdehyde(MDA) in seminal plasma was lower than that in control group(P<0.05);the IIEF-5 and CIPE scores of the observation group were higher than those of the control group(P<0.05);and there was no significant difference in the total incidence of complications between the two groups(P>0.05). Conclusion: For refractory HSS patients, the therapeutic effect of TSV is better than that of the ultrasound-guided seminal vesicle puncture and catheterization, which can effectively improve sperm quality and promote sexual function recovery of patients.
作者
杜广建
王灵点
魏威
DU Guangjian;WANG Lingdian;WEI Wei(Dept.of Urological Surgery,Xinyang People′s Hospital,Xinyang 464100;Dept.of Urological Surgery,Henan Provincial People′s Hospital,Zhengzhou 450000,China)
出处
《华夏医学》
CAS
2022年第5期97-102,共6页
Acta Medicinae Sinica
关键词
尿道精囊镜技术
顽固性血精症
精子质量
性功能
transurethral seminal vesiculoscopy(TSV)
refractory hemospermia syndrome(HSS)
sperm quality
sexual function
