摘要
目的:探讨颈脑一体化超声联合红细胞分布宽度检测对冠心病的诊断价值。方法:选取2019年1月至2020年12月我院心脏内科冠脉造影检查(CAG)确诊为冠状动脉狭窄性病变的80例患者为观察组,选取经冠脉造影诊断的80例无冠状动脉狭窄者做为对照组,比较各组经颅多普勒超声(TCD)检测参数(平均流速Vm)、经颈动脉血管超声检测参数(IMT)、红细胞分布宽度(RDW)水平。结果:观察组的MCA、ACA、PCA的平均流速(Vm)、颈总动脉内-中膜厚度(IMT)、RDW水平明显高于对照组(P<0.05)。Vm、IMT、RDW以及联合检测诊断冠心病ROC曲线下面积分别为0.83、0.81、0.77、0.91,各自诊断冠心病的ROC曲线下面积比较差异有统计学意义(P<0.05)。当同时存在Vm≥2.03m/s、IMT≥1.05mm、RDW水平≥14.65%时诊断冠心病诊断灵敏度为91.25%,特异度为98.75%,平行联合检测灵敏度、特异度明显优于一般单项测试(P<0.05)。结论:颈脑一体化超声联合与红细胞分布宽度联合测定的检测参数水平,与冠心病的发生密切相关,对冠心病的确诊有很大的诊断价值,有较大的经济效益与社会价值。
Objective:To explore the diagnostic value of cervical cerebral integrated ultrasound combined with red blood cell distribution width in coronary heart disease.Methods:80 patients with coronary artery stenosis diagnosed by coronary angiography(CAG)in the Department of Cardiology of our hospital from January 2019 to December 2020 were selected as the observation group,and 80 patients without coronary artery stenosis diagnosed by coronary angiography were selected as the control group.The levels of transcranial Doppler ultrasound(TCD)detection parameters(mean flow velocity VM),transcranial vascular ultrasound detection parameters(IMT)and red blood cell distribution width(RDW)in each group were compared.Results:The mean flow velocity(VM),common carotid artery intima-media thickness(IMT)and RDW levels of MCA,ACA and PCA in the observation group were significantly higher than those in the control group(P<0.05).The area under the ROC curve of VM,IMT,RDW and combined detection for diagnosing coronary heart disease were 0.83,0.81,0.77 and 0.91,respectively.There were statistically significant differences in the area under the ROC curve of each diagnosis of coronary heart disease(P<0.05).When VM≥2.03m/s,IMT≥1.05mm and RDW≥14.65%were present at the same time,the diagnostic sensitivity and specificity were 91.25%and 98.75%,respectively.The sensitivity and specificity of parallel combined detection were significantly better than that of general single test(P<0.05).Conclusion:The level of detection parameters determined by cervical cerebral integrated ultrasound combined with red blood cell distribution width is closely related to the occurrence of coronary heart disease.It has great diagnostic value for the diagnosis of coronary heart disease,and has great economic and social value.
作者
沈健
张皓然
王枫
刘艳伟
李莎
杨绍石
SHEN Jian;ZHANG Haoran;WANG Feng(The Affiliated Hospital of Chengde Medical University,Hebei Chengde 067000,China)
出处
《河北医学》
CAS
2022年第11期1869-1873,共5页
Hebei Medicine
基金
河北省承德市科学技术研究与发展计划项目,(编号:202006A081)。
关键词
经颅多普勒超声
颈动脉血管超声
红细胞分布宽度
冠心病
Transcranial doppler ultrasound
Carotid artery ultrasound
Red blood cell distribution width
Coronary heart disease
