摘要
目的:探讨重复经颅磁刺激(repetitive transcranial magnetic stimulation,rTMS)对脑卒中患者步态的影响。方法:检索电子数据库国内外有关rTMS对脑卒中患者步态影响的文献,统计学分析运用RevMan 5.4软件。共纳入共11项研究,共计350例脑卒中患者。观察组采用rTMS或rTMS配合其他康复治疗,对照组采用假刺激或假刺激配合其他康复治疗。结果:Meta分析结果显示:与对照组相比,观察组步行速度[MD=10.70,95%CI(7.67,13.73),Z=6.92,P<0.001],步频[MD=7.14,95%CI(4.80,9.48),Z=5.98,P<0.001]、6分钟步行测试,[MD=24.77,95%CI(13.61,35.93),Z=4.35,P<0.001],10米步行试验,[MD=-3.47,95%CI(-4.77,-2.16),Z=5.19,P<0.001],合并效应差异显著,计时“起立-行走”测试显示与对照组相比没有显著差异,[MD=-4.83,95%CI(-9.58,-0.08),Z=1.99,P=0.05]。结论:rTMS联合其他康复治疗方法可以有效地提高脑卒中患者的步行速度,改善脑卒中患者的步态,对下肢运动功能的恢复有积极作用。
Objective:To study the effect of repetitive transcranial magnetic stimulation(rTMS)on the gait of apoplexy patients.Methods:The electronic database was searched for the literature on the effect of rTMS on stroke gait at home and abroad,and the statistical analysis was done by Revman 5.4 software.There were 11 studies of 350 patients.The observation group was treated with rTMS or rTMS and other rehabilitation treatments,while the control group was treated with false stimulation or false stimulation and other rehabilitation treatments.Results:Meta analysis revealed there was significant difference in merger effect between observation group and control group:the velocity[MD=10.70,95%CI(7.67,13.73),z=6.92,P<0.001],step frequency[MD=7.14,95%CI(4.80,9.48),z=5.98,P<0.001],6-min walking test[MD=24.77,95%CI(13.61,35.93),z=4.35,P<0.001],and 10 meter walking test[MD=-3.47,95%CI(-4.77,-2.16),z=5.19,P<0.001].There was no significant difference in up-walking test between two groups[MD=-4.83,95%CI(-9.58,-0.08),Z=1.99,P=0.05].Conclusion:The rTMS combined with other rehabilitation treatments can increase the velocity of stroke patients and enhance the gait of stroke patients.It has a positive effect on the resume of lower limb motor function.
出处
《中国康复》
2022年第11期677-683,共7页
Chinese Journal of Rehabilitation
基金
吉林省科技发展计划基金项目(20190303171SF)。
关键词
META分析
重复经颅磁刺激
脑卒中
步态
Meta analysis
repetitive transcranial magnetic stimulation
stroke
gait