摘要
本研究探讨超声引导下甲状腺细针穿刺活检(US-FNAB)对甲状腺微小乳头状癌(PTMC)的诊断价值。选取经病理学检查确诊的203例甲状腺微小结节患者(203个结节)作为研究对象,所有患者均接受了US-FNAB检查,分析不同细胞学特征的甲状腺微小结节与甲状腺Bethesda分类的关系,并以病理学检查结果作为金标准,分析US-FNAB诊断PTMC的价值。根据甲状腺Bethesda分类标准,其中Ⅰ类结节0个、Ⅱ类结节33个、Ⅲ类结节49个、Ⅳ类结节51个、Ⅴ类结节40个、Ⅵ类结节30个。恶性甲状腺结节中实性结节、低回声结节、结节边界模糊、结节纵横径比≥1的占比均大于良性结节(P<0.05);US-FNAB鉴别诊断PTMC与甲状腺良性结节的灵敏度为85.29%、特异度为91.11%;超声鉴别诊断PTMC与甲状腺良性结节的灵敏度为75.00%、特异度为83.70%。US-FNAB对PTMC的诊断价值高于超声检查,对于制定临床个体化治疗方案具有重要意义。
This study investigated the diagnostic value of ultrasound-guided thyroid fine-needle aspiration biopsy(US-FNAB)for papillary thyroid microcarcinoma(PTMC).A total of 203 patients(203 nodules)with thyroid micronodules confirmed by pathological examination were selected.All patients underwent US-FNAB examination.The relationship between thyroid micronodules with different cytological characteristics and Bethesda classification of thyroid was analyzed.The pathological examination results were used as the gold standard to analyze the value of US-FNAB in the diagnosis of PTMC.According to the Bethesda classification of thyroid,there were 0 nodules of classⅠ,33 nodules of classⅡ,49 nodules of classⅢ,51 nodules of classⅣ,40 nodules of classⅤ,and 30 nodules of classⅥ.The proportion of solid nodules,hypoechoic nodules,nodules with blurred borders,and nodule aspect ratio≥1 in malignant thyroid nodules was higher than that in benign nodules(P<0.05);US-FNAB The sensitivity and specificity of differential diagnosis of PTMC and benign thyroid nodules were 85.29%and 91.11%;the sensitivity and specificity of ultrasound in differential diagnosis of PTMC and benign thyroid nodules were 75.00%and 83.70%.The diagnostic value of US-FNAB for PTMC is higher than that of ultrasonography,and it is of great significance for the formulation of clinical individualized treatment plans.
作者
王菁
刘莹
崔权哲
周洋
WANG Jing;LIU Ying;CUI Quanzhe;ZHOU Yang(Department of Ultrasound,The Third People’s Hospital of Chengdu,Chengdu 610014,Sichuan,P.R.China;Department of Pathology,The Third People’s Hospital of Chengdu,Chengdu 610014,Sichuan,P.R.China)
出处
《影像科学与光化学》
CAS
北大核心
2022年第6期1423-1427,共5页
Imaging Science and Photochemistry
关键词
超声引导下甲状腺细针穿刺活检
甲状腺微小乳头状癌
甲状腺微小结节
诊断价值
ultrasound-guided thyroid fine needle aspiration biopsy
thyroid micropapillary carcinoma
diagnosis
thyroid micronodules
diagnostic value
