摘要
目的分析宫颈活检组织病理学与液基细胞学检测诊断宫颈上皮内瘤变的价值。方法选择2020年1月至2022年4月在浙江大学医学院附属第一医院接受治疗的122例宫颈上皮内瘤变患者,对所选患者进行阴道镜下宫颈活检组织病理学检查和液基细胞学检测,以宫颈锥切术检验的病理结果评估宫颈活检组织病理学检测和液基细胞学检测的准确性。结果将宫颈锥切术病理结果作为金标准,金标准检测结果发现阳性患者共58例,占47.54%,阴性患者共64例,占52.46%;宫颈活检组织病理学检测的灵敏度、特异度、准确度均高于液基细胞学检测,差异有统计学意义(P<0.05)。结论宫颈活检组织病理学检测与液基细胞学检测对宫颈上皮内瘤变的诊断有一定参考意义,其中阴道镜下宫颈活检组织病理学检测准确性更高,且创伤较小。
Objective To analyze the value of cervical biopsy histopathology and liquid-based cytology in the detection of cervical intraepithelial neoplasia.Methods A total of 122 patients with cervical intraepithelial neoplasia who were treated in the First Affiliated Hospital Zhejiang University School of Medicine from January 2020 to April 2022 were selected.Colposcopy cervical biopsy histopathology and liquid-based cytology were performed on selected patients,and the pathological results of cervical conization were used to evaluate the accuracy of cervical biopsy histopathology and liquid-based cytology.Results The pathological results of cervical conization were used as the gold standard.The gold standard test results found that there were 58 positive patients,accounting for 47.54%,and 64 negative patients,accounting for 52.46%.The sensitivity,specificity and accuracy of cervical biopsy histopathological detection were all higher than those of liquid-based cytology,the differences were statistically significant(P<0.05).Conclusion The histopathological detection of cervical biopsy and liquid-based cytology have certain reference significance for the diagnosis of cervical intraepithelial neoplasia,but the histopathological detection of cervical biopsy under colposcopy is more accurate and less traumatic.
作者
贾燕鸿
李央
JIA Yanhong;LI Yang(Department of Obstetrics,the First Affiliated Hospital Zhejiang University School of Medicine,Zhejiang Province,Hangzhou 311100,China)
出处
《妇儿健康导刊》
2022年第11期30-32,39,共4页
JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE
关键词
宫颈活检组织病理学
液基细胞学检测
宫颈上皮内瘤变
Cervical biopsy histopathology
Liquid-based cytology
Cervical intraepithelial neoplasia
