摘要
目的分析青岛市中心医院癌因性疼痛(简称癌痛)患者麻醉药物的处方及使用情况。方法收集1401份癌痛患者麻醉药物处方,采用世界卫生组织(WHO)推荐的限定日剂量并参照《新编药物学》、药品说明书及青岛市中心医院各类癌痛治疗药物利用指数(DUI),对青岛市中心医院癌痛患者麻醉药品处方情况进行合理性评价及分析。结果青岛市中心医院癌痛患者处方中共涉及13种麻醉药品,用药方法包括口服、注射、贴剂及栓剂4种。在全部处方中,用量最多的麻醉药品是盐酸吗啡片,占22.91%,其次为盐酸羟考酮缓释片和氨酚羟考酮片,分别占15.85%、15.63%。癌痛患者的麻醉药品总用药频度为9782.24,其中盐酸羟考酮缓释片的用药频度最高,为3386.56,其次分别为氨酚羟考酮片、盐酸吗啡片和盐酸曲马多缓释片。1401份中共154份处方存在不合理用药情况,占总处方的10.99%(154/1401),共有5种不合理用药情况,其中以药品使用频次不合理及药品适应证不合理最为常见,分别占不合理处方的43.51%和40.26%。结论青岛市中心医院癌痛患者麻醉药物处方的使用情况基本合理,医师和药师应更加重视麻醉药品用药频次与管理。
Objective To analyze the use and prescription of anesthetic drugs for patients with cancer pain in Qingdao Central Hospital. Method A total of 1401 prescriptions of anesthetic drugs for cancer pain patients were collected,and the rationality of the prescriptions of anesthetic drugs for cancer pain patients in Qingdao Central Hospital was evaluated and analyzed by using the defined daily dose recommended by the World Health Organization(WHO) and referring to the New Pharmacology, the drug manual, and the drug utilization index(DUI) of various drugs for cancer pain treatment in Qingdao Central Hospital. Result There were 13 kinds and 4 types(oral formulation, injection formulation,patch and suppository) of narcotic drugs involved in the prescription for cancer pain patients in Qingdao Central Hospital.Among all the prescriptions, morphine hydrochloride tablets accounted for 22.91%, followed by oxycodone hydrochloride sustained-release tablets and oxycodone paracetamol tablets, accounting for 15.85% and 15.63%, respectively. The total defined daily doses of cancer pain patients was 9782.24, of which oxycodone hydrochloride sustained-release tablets had the highest defined daily doses of 3386.56, followed by paracetamol oxycodone tablets, morphine hydrochloride tablets and tramadol hydrochloride sustained-release tablets. In 1401 prescriptions, 154 prescriptions had irrational drug use,accounting for 10.99%(154/1401). There were 5 kinds of irrational drug use, among which the irrational frequency of drug use and irrational drug indications were the most common, accounting for 43.51% and 40.26%, respectively. CCoonncclluu-sion The use of anesthetic prescriptions for cancer pain patients in Qingdao Central Hospital is basically reasonable, and doctors and pharmacists should pay more attention to the frequency and management of anesthetic drug use.
作者
孟向尚
谭秀彦
崔晓
周恒燕
MENG Xiangshang;TAN Xiuyan;CUI Xiao;ZHOU Hengyan(Department of Pharmacy,Qingdao Central Hospital,Qingdao 266071,Shandong,China)
出处
《癌症进展》
2022年第19期1983-1985,共3页
Oncology Progress
关键词
癌因性疼痛
麻醉药物
合理用药
处方分析
cancer pain
anesthetic drug
rational drug use
prescription analysis
