摘要
目的观察高度近视患者行飞秒激光小切口角膜基质透镜取出术(SMILE)和飞秒激光制瓣准分子激光原位角膜磨镶术(FS-LASIK)术后角膜光密度的变化规律及其意义。方法选取2018年11月至2020年11月在宁夏眼科医院行SMILE和FS-LASIK手术的高度近视患者,其中SMILE组40例40眼,FS-LASIK组41例41眼。应用Pentacam三维眼前节分析系统于术前,术后1、3、6个月以角膜顶点为中心,分别测量0~2 mm、2~6 mm、6~10 mm直径以及角膜的前、中、后及全层的角膜光密度。结果SMILE与FS-LASIK两组术后6个月不同直径及层次的角膜光密度均低于术前(P均<0.05)。两组间术后1个月6~10 mm前层及总体角膜光密度差别均具有统计学意义(P均<0.05),于术后3个月差异消失。术后1个月,FS-LASIK组0~2 mm、2~6 mm、6~10 mm前层角膜光密度与基质切削深度均存在正相关(r=0.451、0.506、0.411;P=0.004、0.001、0.009)。结论高度近视患者手术区域角膜光密度在SMILE与FS-LASIK术后早期均出现一过性上升,随着时间推移,两组角膜光密度均较术前降低。FS-LASIK组术后早期前层角膜光密度与切削深度存在正相关。
Objective To observe the changes of corneal densitometry(CD)after small incision lenticule extraction(SMILE)and femtosecond laser-assisted laser in situkeratomileusis(FS-LASIK)in patients with high myopia and its significance.Methods High-myopia patients who received SMILE and FS-LASIK surgery in the Ningxia Eye Hospital from November,2018 to November,2020 were selected,including 40 patients(40 eyes)in SMILE group and 41 patients(41 eyes)in FS-LASIK group.The CD was measured with the Pentacam Scheimpflug system before surgery and postoperatively at 1、3 and 6 months.The diameter ranges of 0-2 mm、2-6 mm、6-10 mm as well as the anterior,middle,posterior and full-thickness CD with the apex of the cornea were recorded.Results At 6 months,in both of SMILE and FS-LASIK group,there were significant differences between the preoperative and postoperative CD values in different diameter ranges and corneal layers,and the values were lower than preoperative(P all<0.05).At 1 month,there were statistical significance of CD in 6-10mm anterior layer and total layer between the two groups(P all<0.05),however,the differences were disappeared at 3 months.The anterior layers of CD at 1 month was found positively correlated with ablation depth for the FS-LASIK group(r=0.451、0.506、0.411;P=0.004、0.001、0.009).Conslusion In the early stage,the surgically area of CD increased temporarily after SMILE and FS-LASIK surgery for patients with high myopia.However,the CD decreased over time until lower than preoperative level.There was a positive correlation between anterior layers of the CD and ablation depth after FS-LASIK.
作者
陈琳
薛雅珺
田恬
蔡博
李帅
马丽梅
秦艺璇
庄文娟
CHEN Lin;XUE Yajun;TIAN Tian;CAI Bo;LI Shuai;MA Limei;QIN Yixuan;ZHUANG Wenjuan(The Third Clinical Medicine College,Ningxia Medical University,Yinchuan 750004,China;Department of Ophthalmology,Ningxia Eye Hospital,People's Hospital of Ningxia Hui Autonomous Region,First Affiliated Hospital of Northwest University for Nationalities,Yinchuan 750001,China)
出处
《宁夏医科大学学报》
2022年第9期932-937,共6页
Journal of Ningxia Medical University
基金
宁夏回族自治区科技厅重点研发计划(2019BEG03016)。
