摘要
目的:研究探讨腹腔镜下子宫肌瘤剔除术(LSHM)对围绝经期子宫肌瘤(UF)患者卵巢功能的影响。方法:选择2017年6月-2020年6月惠州市第一妇幼保健院妇科的围绝经期UF患者103例作为研究对象,采用随机数表法将其分为对照组51例和研究组52例。对照组进行腹腔镜下全子宫切除术(TLH),研究组进行LSHM。对比两组患者手术前后的卵巢功能、生活质量、围绝经期症状发生情况。结果:术前两组患者的促黄体生成素(LH)、促卵泡激素(FSH)、雌二醇(E2)比较,差异无统计学意义(t=0.414、0.107、0.817,P>0.05),术后研究组的LH、FSH低于对照组,E2高于对照组,差异有统计学意义(t=31.464、18.149、16.018,P<0.05)。术前两组患者生理健康、心理健康、生活质量使用简明健康调查量表(SF-36)总分比较,差异无统计学意义(t=0.551、0.018、0.291,P>0.05),术后研究组的生理健康、心理健康、SF-36总分高于对照组,差异有统计学意义(t=9.705、4.583、7.119,P<0.05);研究组的围绝经期症状发生率(9.61%)低于对照组(27.45%),差异有统计学意义(χ^(2)=5.444,P<0.05)。结论:LSHM相比TLH对围绝经期UF患者卵巢功能的影响较小,患者术后的生活质量较高,能够减少术后围绝经期症状的发生。
Objective:To investigate the effect of laparoscopic myomectomy(LSHM)on ovarian function in perimenopausal patients with uterine fibroids(UF).Methods:A total of 103 perimenopausal UF patients in the hospital from June 2017 to June 2020 were selected as the research subjects,and they were divided into 51 cases in the control group and 52 cases in the research group by the random number table method.The control group underwent laparoscopic total hysterectomy(TLH),and the study group underwent LSHM.The ovarian function(LH,FSH,E2),quality of life(SF-36),perimenopausal symptoms(flushing,abnormal menstruation,osteoporosis)before and after surgery were compared between the two groups.Results:There was no statistically significant difference in luteinizing hormone(LH),follicle-stimulating hormone(FSH),and estradiol(E2)between the two groups before surgery(t=0.414,0.107,0.817,P>0.05).After operation,LH and FSH in the study group were lower than those in the control group,and E2 was higher than that in the control group,with statistically significant differences(t=31.464,18.149,16.018,P<0.05).Before surgery,there was no statistically significant difference in the total scores of physical health,mental health and quality of life between the two groups using the Brief Health Survey Scale(SF-36)(t=0.551,0.018,0.291,P>0.05).The physical health,mental health and SF-36 total score of the study group were higher than those of the control group after operation,and the difference was statistically significant(t=9.705,4.583,7.119,P<0.05).The incidence of perimenopausal symptoms in the study group(9.61%)was lower than that in the control group(27.45%),and the difference was statistically significant(χ^(2)=5.444,P<0.05).Conclusion:Compared with TLH,LSHM has less effect on ovarian function in perimenopausal UF patients,and patients have higher quality of life after surgery,and can reduce the occurrence of postoperative perimenopausal symptoms,which is worthy of application.
作者
李裕华
黄芳
欧阳彦兰
LI Yu-hua;HUANG Fang;OUYANG Yan-lan(Department of Gynecology,Huizhou First Maternal and Child Health Care Hospital,Huizhou,Guangdong,516000,China)
出处
《黑龙江医学》
2022年第19期2336-2338,共3页
Heilongjiang Medical Journal
