摘要
目的探究与分析苍附导痰汤治疗痰湿内阻证肥胖型多囊卵巢综合征(PCOS)的临床效果。方法选取山东省聊城市中医医院2019年1月至2021年1月收治的痰湿内阻证肥胖型PCOS患者120例,按照随机数字表法分为观察组和对照组,各60例。对照组给予盐酸二甲双胍肠溶片治疗,在对照组基础上,观察组加用苍附导痰汤治疗,两组均连续治疗3个月。比较两组临床疗效、治疗前后体重指数(BMI)、糖代谢指标、血脂代谢指标变化及排卵情况。结果观察组临床总有效率及排卵率高于对照组(P<0.05)。治疗后两组BMI、空腹胰岛素、空腹血糖、血清总胆固醇、三酰甘油、低密度脂蛋白胆固醇较治疗前降低,且观察组低于对照组,高密度脂蛋白胆固醇较治疗前升高,且观察组高于对照组(P<0.05)。结论苍附导痰汤治疗痰湿内阻证肥胖型PCOS具有较好的临床效果,可有效降低患者的BMI值,调节糖脂代谢指标,还可在一定程度上改善排卵情况。
Objective To explore and analyze the clinical effect of Cangfu Daotan Decoction in the treatment of obesity-type polycystic ovary syndrome(PCOS)with phlegm-damp internal resistance syndrome.Methods A total of 120 obese PCOS patients with phlegm-humidity internal resistance syndrome admitted to Liaocheng Hospital of Traditional Chinese Medicine in Shandong Province from January 2019 to January 2021 were selected and they were divided into observation group and control group according to the random number table method,with 60 cases in each group.The control group was treated with Metformin Hydrochloride Enteric-coated Tablets,on the basis of the control group,the observation group was treated with Cangfu Daotan Decoction,both groups were treated for three months.The clinical efficacy,body mass index(BMI),glucose metabolism index,lipid metabolism index,and ovulation before and after treatment were compared between the two groups.Results The total effective rate and ovulation rate of the observation group were higher than those of the control group(P<0.05).After treatment,the values of BMI,fasting insulin,fasting blood glucose,total cholesterol,triacylglycerol,and low density lipoprotein cholesterol in the two groups were lower than those before treatment,and observation group were lower than those in the control group,the high density lipoprotein cholesterol was increased than those befere treatment,and the observation group was higher than those in the control group(P<0.05).Conclusion Cangfu Daotan Decoction in the treatment of obese PCOS with phlegm-damp internal resistance syndrome patients can have a good clinical effect,can effectively reduce the patient’s BMI value,adjust the glucose and lipid metabolism indicators,and can also promote and improve ovulation to a certain extent.
作者
单珂
高慧
SHAN Ke;GAO Hui(Department of Obstetrics and Gynecology,Liaocheng Hospital of Traditional Chinese Medicine,Shandong Province,Liaocheng 252000,China)
出处
《中国医药导报》
CAS
2022年第29期130-133,143,共5页
China Medical Herald
基金
山东省医药卫生科技发展计划项目(2019WS613)。
关键词
苍附导痰汤
肥胖
多囊卵巢综合征
痰湿内阻证
糖脂代谢
排卵率
Cangfudaotan Decoction
Obesity
Polycystic ovary syndrome
Phlegm-damp internal resistance syndrome
Glucose and lipid metabolism
Ovulation rate
