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改良根治术与保乳手术对早期乳腺癌的临床效果、术后并发症及生活质量的影响分析 被引量:30

Clinical effect,postoperative complications and quality of life of modified radical mastectomy and breast-conserving surgery on early breast cancer
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摘要 目的:分别使用改良根治术与保乳术对早期乳腺癌患者进行治疗,观察其并发症及生活质量。方法:将我院(邵阳学院附属第一医院)收治的早期乳腺癌共106例患者作为本次研究对象,随机分为两组,改良根治术在对照组患者中施行,观察组行保乳术,比较两组患者的临床效果、术后并发症及生活质量。结果:观察组患者手术实施时间明显短于对照组、手术过程出血总量明显低于对照组。观察组患者术后住院时间及引流液量均少于对照组。两组患者术后并发症,如呼吸抑制、低血压、呕吐、恶心、瘙痒等方面发生率差异无统计学意义。两组随访1年复发率、远处转移率、生存率差异均无统计学意义。两组患者术前FACT-B评分差异均无统计学意义。观察组术后6个月FACT-B评分高于对照组。结论:早期乳腺癌行保乳手术的手术时间明显较短,促进患者术后的恢复,并有利于患者生活质量的提高,适于在临床推广应用。 Objective To observe the effect of modified radical mastectomy and breast conserving surgery on complications and quality of life for the patients of early breast cancer.Methods Patients of early breast cancer with the number of 106 were treated in our hospital (the First Affiliated Hospital of Shaoyang University).They were considered as study objects and then separated into two groups randomly,named control group and observation group.The modified radical mastectomy was performed in the control group,and the breast-conserving surgery was used in the observation group.The clinical effects,postoperative complications and complications of the two groups were observed.impact on quality of life.Results The difference presented statistical meaning in the comparisons of the operation time,intraoperative blood loss,postoperative hospital stay and drainage fluid volume between both groups after observation,the patients of the treatment group was better than that in the control group.The difference presented no statistical meaning in the comparisons of the incidences of postoperative hypotension,respiratory depression,nausea,vomiting and pruritus between both groups after treating.The difference presented no statistical meaning in the comparisons of the recurrence rate,distant metastasis rate and survival rate between both groups during 1-year follow-up.The difference presented no statistical meaning in the preoperative FACT-B score between both groups.The difference presented statistical meaning in the comparisons of the FACT-B score between both groups after operation,the observation group was superior to the control group.Conclusion The operation time of breast-conserving surgery for early breast cancer is significantly shorter,which is beneficial to the postoperative recovery of patients and improves the postoperative quality of life,and it is worth of applying in clinic.
作者 袁忠 马海南 王科军 Yuan Zhong;Ma Hai-nan;Wang Ke-jun(Breast Nail Surgery,The First Affiliated Hospital of Shaoyang University,Shaoyang,422000 China)
出处 《晓庄学院学报(医学版)》 2022年第4期91-94,共4页 Journal of Hunan Normal University(Medical Sciences)
关键词 全身麻醉 前锯肌神经阻滞 乳腺癌 生存质量 疼痛 general anesthesia serratus anterior nerve block breast cancer quality of life pain
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