摘要
BACKGROUND Although extraintestinal manifestations of inflammatory bowel disease(IBD) are well documented,myocarditis has only rarely been reported as an extraintestinal manifestation,and it can be fatal.The various clinical presentations and causes of myocarditis in IBD patients complicate making a correct and timely diagnosis.CASE SUMMARY Here we report a 15-year-old boy who presented with myocarditis as the initial presentation of a relapse of ulcerative colitis.In reviewing the literature for cases of myocarditis complicating IBD,we found 21 other cases,allowing us to expand our understanding of the clinical presentation,diagnosis,management,and outcomes of this rare condition.The most frequent diagnostic clues for myocarditis in IBD patients are dyspnea,chest pain,tachycardia,raised cardiac biomarkers,and abnormalities on trans-thoracic echocardiography.Additionally,we discuss the etiology of myocarditis in IBD patients,which include an extraintestinal manifestation,the adverse effects of mesalamine and infliximab,selenium deficiency,and infection,to help provide a framework for diagnosis and management.CONCLUSION Myocarditis as an extraintestinal manifestation of IBD can be life-threatening.Trans-thoracic echocardiogram and cardiac magnetic resonance may assist its diagnosis.
基金
Supported by China Medical Board Open Competition Program,No. 20-384
National Major Science and Technology Projects of China,No. 2020YFC0841300。
