摘要
目的:分析非小细胞肺癌(NSCLC)合并慢性阻塞性肺疾病(COPD)患者的运动耐量及通气效率状况。方法:选择65例NSCLC合并COPD患者为观察组进行研究,选择同期接诊的65例单纯NSCLC患者为对照组。回顾性分析两组患者的临床资料,比较两组的临床症状、肺功能指标、运动耐量及通气效率。结果:观察组咳嗽、咯痰、呼吸困难、咯血、消瘦的发生率均显著高于对照组,差异有统计学意义(P<0.05)。观察组用力肺活量(FVC)、第1秒用力呼气容积(FEV1)、预测值百分比(FEV1)%水平均显著低于对照组,差异有统计学意义(P<0.05)。观察组的6分钟步行试验(6MWT)(305.18±20.86)m,显著低于对照组的(357.56±21.54)m,差异有统计学意义(P<0.05)。观察组的通气量(VE)、潮气量(VT)水平均显著低于对照组,二氧化碳通气当量(VE/VCO)、柱氧量(VO)、心率(HR)水平均显著高于对照组,差异有统计学意义(P<0.05)。结论:NSCLC合并COPD患者的通气效率显著低于单纯NSCLC患者,降低其运动耐量,医生需要在诊治NSCLC时,早发现并规范化治疗COPD,改善预后。
Objective To analyze the exercise tolerance and ventilation efficiency of patients with non-small cell lung cancer(NSCLC) combined with chronic obstructive pulmonary disease(COPD).Method The 65 patients with NSCLC and COPD were selected as the observation group for the study, and the 65 patients with simple NSCLC admitted at the same time in our hospital were selected as the control group. The clinical data of the two groups of patients were retrospectively analyzed, and the clinical symptoms, pulmonary function indexes, exercise tolerance and ventilation efficiency of the two groups were compared.Results The incidence of cough, sputum expectoration, dyspnea, hemoptysis, and weight loss in the observation group were significantly higher than those in the control group(P<0.05). The FVC, FEV1 and FEV1% levels of the observation group were significantly lower than those of the control group(P<0.05). The 6 MWT(305.18±20.86)m of the observation group was significantly lower than that of the control group(357.56±21.54)m(P<0.05). The VE and VT levels of the observation group were significantly lower than those of the control group, and the levels of VE/VCO2,VO2, and HR were significantly higher than those of the control group(P<0.05).Conclusion The ventilation efficiency of patients with NSCLC and COPD is significantly lower than that of patients with NSCLC alone, which reduces their exercise tolerance. Doctors need to diagnose and treat NSCLC early and standardize the treatment of COPD to improve the prognosis.
作者
卢娜
LU Na(Wuhan Hankou Hospital,Wuhan 430012,China)
出处
《吉林医学》
CAS
2022年第9期2360-2362,共3页
Jilin Medical Journal
关键词
非小细胞肺癌
慢性阻塞性肺疾病
肺功能
运动耐量
通气效率
Non-small cell lung cancer
Chronic obstructive pulmonary disease
Lung function
Exercise tolerance
Ventilation efficiency
