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Application of adipose-derived stem cells in treatment of neurodegenerative diseases:A review

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摘要 Neurodegenerative diseases are a class of progressive degenerative diseases that mainly include neuronal function decline and loss,such as Alzheimer's disease(AD);Cerebral troke;Parkinson's disease(PD);etc.These diseases are difficult to cure and seriously affect people's quality of life.Adipose derived stem cells(ADSCs)are derived from mesenchymal stem cells isolated and purified from adipose tissue.They have the characteristics of multidirectional differentiation and are widely used in the treatment of neurodegenerative diseases.Therefore,the use of ADSCs to treat this type of disease has potential application value.This article discusses the role of ADSCs in neurodegenerative diseases and their regeneration characteristics,and discusses the current clinical applications and future challenges of ADSCs,in order to provide references for the clinical application of ADSCs.
作者 Fang-Fang Liu Hao-Fei Fan Qing-Man Li Feng Guo Xi-Nan Yi Hai-Ying Zhang
机构地区 Hainan Key Laboratory for Research and Transformation of Tropical Brain Science
出处 《Journal of Hainan Medical University》 2022年第14期53-58,共6页 海南医学院学报（英文版）
基金 National Natural Science Foundation of China(No.81660224 81100246) Hainan Provincial Key Research and Development Project(No.ZDYF2017120) Hainan Provincial Postgraduates’Innovation Project(No.Hys2019-288).
关键词 Neurodegenerative diseases ADSCS AD PD
分类号 R575 [医药卫生—消化系统] R459.7 [医药卫生—急诊医学]
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Journal of Hainan Medical University
2022年 第14期

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