摘要
目的回顾性分析结肠息肉术后复发的影响因素。方法选取2014年5月至2019年5月于上海中医药大学附属普陀医院住院并行内镜下治疗的416例结肠息肉患者,根据术后是否复发将其分为复发组(216例)和未复发组(200例),回顾性收集患者的临床资料,分析结肠息肉术后复发的影响因素。结果复发组男性、年龄≥60岁、非酒精性脂肪性肝病、高血压、2型糖尿病、手术方式为氩等离子体凝固术(APC)及APC联合高频电凝切除术、息肉数目≥3个、息肉直径≥10 mm、多部位、腺瘤占比及体重指数(BMI)、尿酸(UA)、甘油三酯(TG)、高密度脂蛋白(HDL)水平均高于未复发组,差异有统计学意义(P<0.05)。多因素分析结果显示,年龄≥60岁、非酒精性脂肪性肝病、高血压、高BMI、息肉数目≥3个、息肉直径≥10 mm、多部位息肉、腺瘤均为结肠息肉复发的独立危险因素(OR>1,P<0.05)。结论年龄≥60岁、非酒精性脂肪性肝病、高血压、息肉数目≥3个、息肉直径≥10 mm、多部位息肉、腺瘤、高BMI是结肠息肉复发的独立影响因素,可能与结肠息肉的复发密切相关,可为国内临床医师指导结肠息肉患者的随访工作提供一定的参考价值。
Objective To retrospectively analyze the influencing factors of postoperative recurrence of colonic polyps after treatment.Methods A total of 416 patients with colonic polyps hospitalized and received endoscopic treatment in Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine from May 2014 to May 2019 were selected.The patients were divided into the recurrence group(216 cases)and the non-recurrence group(200 cases)according to the postoperative recurrence.The clinical data of the patients were retrospectively collected to analyze the influencing factors of postoperative recurrence of colonic polyps.Results The proportion of male,age≥60 years,non-alcoholic fatty liver disease,hypertension,type 2 diabetes mellitus,operation method of argon-plasma coagulation(APC)and APC combined with high frequency electrical polypectomy,number of polyps≥3,diameter of polyps≥10 mm,multiple sites,adenoma,and the levels of body mass index(BMI),uric acid(UA),triglyceride(TG),high density lipoprotein(HDL)in the recurrence group were all higher than those in the non-recurrence group,and the differences were statistically significant(P<0.05).Multivariate analysis showed that age≥60 years,non-alcoholic fatty liver disease,hypertension,high BMI,number of polyps≥3,diameter of polyps≥10 mm,multiple sites,and adenoma were independent risk factors for colon polyp recurrence(OR>1,P<0.05).Conclusion Age≥60 years,non-alcoholic fatty liver disease,hypertension,number of polyps≥3,diameter of polyps≥10 mm,multiple sites,adenoma,high BMI are independent influence factors of recurrence of colonic polyps,may be closely related with the recurrence of colonic polyps,for domestic clinicians guide patients with colonic polyps of follow-up work provide certain reference value.
作者
高静静
鲁仕昱
杜晟楠
袁乙富
蒋元烨
曹勤
GAO Jingjing;LU Shiyu;DU Shengnan;YUAN Yifu;JIANG Yuanye;CAO Qin(Department of Gastroenterology,Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200062,China)
出处
《中国医药导报》
CAS
2022年第23期104-108,共5页
China Medical Herald
基金
国家自然科学基金青年科学基金项目(81703879)
上海市卫计委临床研究专项面上项目项目(201840377、201940449)
上海市普陀区卫生健康系统科技创新项目计划项目(ptkwws201813)
上海中医药大学后备卓越中医人才项目(20D-RC-02)。
关键词
结肠息肉
复发
影响因素
Colonic polyps
Recurrence
Influencing factors
