摘要
目的:了解本地区女性人群不同年龄段、不同下生殖道状况的宫颈病变分布特点。方法:选取2020年6月至2020年12月在武汉大学中南医院妇产科就诊的妇女共4 966人进行宫颈液基薄层细胞学(TCT)检测,分析不同年龄段、不同下生殖道状况的宫颈病变状况。结果:受检妇女人群TCT阳性率2.52%,其中意义不明确的非典型鳞状上皮细胞(ASC-US)所占比例最大(59.2%)。按照年龄段分布进行分析,≥55~<65岁年龄组阳性检出率最高(6.50%),且与其他年龄较小组相比差异具有统计学意义(P<0.01)。而根据下生殖道状况分组统计,HPV感染组和宫颈肿瘤组TCT阳性结果检出率较高(9.09%,10.91%),且与其他组相比差异具有统计学意义(P<0.01)。结论:本地区不同年龄段、不同下生殖道状况的宫颈病变情况存在差异,应加强25岁以上女性和有相关宫颈疾病患者宫颈癌的筛查力度,以便尽早发现宫颈癌前病变和宫颈癌,做到早预防、早诊断、早治疗。
Objective: To study the status of ThinPrep cytology test(TCT)screening in women with different lower genital tract diseases in different age groups in Wuhan, China. Methods: From June 2020to December 2020, 4 966 females in Zhongnan Hospital of Wuhan University were detected by TCT,and the distribution of cervical lesions in different age groups and different lower genital tract diseases were analyzed. Results: Among the 4 966 samples, 125 cases were positive(positive rate 2. 52%), and the proportion of ASC-US in the positive cases was the highest(59. 2%). The positive rate of TCT in aged ≥55 and <65 years group was significantly higher than in other age groups(P<0. 01). The HPV infection group and cervical tumor group showed a significantly higher positive rate of TCT than vaginitis group and cervicitis group did(P<0. 01). Conclusion: Cervical lesions are different in patients with different lower genital tract diseases at different ages. In order to early diagnosis and treatment of cervical precancerous lesions and cervical cancer, efforts should be made to strengthen the cervical cancer screening for women over 25 years old and with lower genital tract diseases.
作者
谢菲
李汉华
庞晓萌
XIE Fei;LI Hanhua;PANG Xiaomeng(Dept.of Obstetrics and Gynecology,Zhongnan Hospital of Wuhan University,Wuhan 430071,Hubei,China)
出处
《武汉大学学报（医学版）》
CAS
2022年第5期838-841,847,共5页
Medical Journal of Wuhan University
基金
湖北省自然科学基金资助项目(编号:ZRMS2021000799)。
