摘要
目的:探究计算机认知矫正治疗在恢复期双相情感障碍患者中的应用效果及对认知功能的影响。方法:选取2019年6月-2021年6月赣州市第三人民医院的80例恢复期双相情感障碍患者,按照随机数字表法将患者分为对照组40例和观察组40例。对照组进行常规治疗与干预,观察组则在对照组的基础上进行计算机认知矫正治疗。比较两组疗效、杨氏躁狂评定量表(YMRS)和汉密尔顿抑郁量表(HAMD)评分、言语记忆测试(HVLT-R)及威斯康辛卡片分类测试(WCST)、同型半胱氨酸(Hcy)及血清淀粉样蛋白A(SAA)水平。结果:观察组总有效率高于对照组(P<0.05)。治疗前,两组YMRS评分、HAMD评分、HVLT-R、WCST、Hcy、SAA水平比较,差异均无统计学意义(P>0.05);治疗后,两组YMRS评分、HAMD评分、HVLT-R、WCST、Hcy、SAA水平均优于治疗前,且观察组均优于对照组,差异均有统计学意义(P<0.05)。结论:计算机认知矫正治疗在恢复期双相情感障碍患者中的应用效果较好,且可有效地改善对患者的认知功能,在恢复期双相情感障碍患者中的应用价值较高。
Objective:To investigate the application effect of computerized cognitive remediation therapy in patients with bipolar disorder at convalescence and its influence on cognitive function.Method:A total of 80 patients with bipolar disorder at convalescence in the Third People’s Hospital of Ganzhou from June 2019 to June 2021 were selected,they were divided into control group(n=40)and observation group(n=40)according to random number table method.The control group received routine treatment and intervention,while the observation group received computerized cognitive remediation therapy on the basis of the control group.Efficacy,Young’s manic rating scale(YMRS)and Hamilton depression scale(HAMD)scores,verbal memory test(HVLT-R)and wisconsin card classification test(WCST),homocysteine(Hcy)and serum amyloid A(SAA)levels were compared between two groups.Result:The total effective rate in observation group was higher than that in control group(P<0.05).Before treatment,there were no significant differences in YMRS scores,HAMD scores,HVLT-R,WCST,Hcy and SAA levels between two groups(P>0.05);after treatment,YMRS scores,HAMD scores,HVLT-R,WCST,Hcy and SAA levels in both groups were better than those before treatment,and those in the observation group were better than those in the control group,the differences were statistically significant(P<0.05).Conclusion:The application effect of computerized cognitive remediation therapy in patients with bipolar disorder at convalescence is better,and it can effectively improve the cognitive function,so its application value in patients with bipolar disorder at convalescence is higher.
作者
江小建
王天明
JIANG Xiaojian;WANG Tianming(The Third People’s Hospital of Ganzhou,Jiangxi Province,Ganzhou 341000,China;不详)
出处
《中国医学创新》
CAS
2022年第23期155-158,共4页
Medical Innovation of China
基金
江西省卫生健康委科技计划项目(20187276)
江西省赣州市科技计划项目(GZ2021ZSF749)。
关键词
计算机认知矫正治疗
恢复期
双相情感障碍
认知功能
Computerized cognitive remediation therapy
Convalescence
Bipolar disorder
Cognitive function
