摘要
目的探讨老年心力衰竭患者合并肺部感染患者的临床预后影响因素,以期为临床治疗提供理论依据。方法选取2021年1月—2022年2月于上海市浦东新区浦南医院收治的136例老年心衰合并肺部感染的患者为研究对象,根据患者入院治疗14d后的存亡情况,将患者分为生存组(108例)和死亡组(28例),收集2组患者的性别、年龄、原发疾病、治疗方法、血液指标和生化指标等情况,分析影响老年心衰合并肺部感染患者临床预后的因素。结果单因素分析结果显示,死亡组患者的白细胞计数水平、肌酐水平、尿素氮水平、PCT水平、D-D水平和Pro-BNP水平显著高于生存组(P<0.05),而生存组的早期联合使用抗生素比例则显著高于死亡组(P<0.05);二元Logistic回归分析显示,高龄、合并糖尿病、高水平Pro-BNP、高水平PCT为老年心衰合并肺部感染患者临床预后的危险因素,早期抗生素联合使用是其保护因素(P<0.05)。结论高龄、合并糖尿病、Pro-BNP水平升高、PCT水平升高可能是老年心衰合并肺部感染患者临床预后的危险因素,应采用针对性的防治措施,以改善老年心衰合并肺部感染患者临床预后状况。
Objective To explore the influencing factors of clinical prognosis in elderly patients with heart failure complicated with pulmonary infectionand provide theoretical basis for clinical treatment.Methods 136elderly patients with heart failure complicated with pulmonary infection treated in Punan Hospital from January2021to February2021were selected as the research subjects.They were divided into survival group(108cases)and death group(28cases)according to their survival condition after14days of hospitalization.The gender,age,primary disease,treatment methods,blood indexes and biochemical indexes of the two groups were collected,and the factors affecting the clinical prognosis of elderly patients with heart failure complicated with pulmonary infection were analyzed.Results Univariate analysis showed that the levels of leukocyte count,creatinine,urea nitrogen,PCT,D-D and pro-BNP in the death group were significantly higher than those in the survival group(P<0.05),while the proportion of early combined use of antibiotics in the survival group was significantly higher than that in the death group(P<0.05).Binary Logistic regression analysis showed that advanced age,combined diabetes,high levels of Pro-BNP,and high levels of PCT were risk factors for clinical prognosisofelderly patients with heart failure complicated with pulmonary infection,and early combined use of antibiotics was a protective factor(P<0.05).Conclusion Advanced age,diabetes,elevated Pro-BNP levels and elevated PCT levels may be the risk factors for the clinical prognosis of elderly patients with heart failure complicated with pulmonary infection.Targeted prevention and treatment measures should be adopted to improve the clinical prognosis of elderly patients with heart failure complicated with pulmonary infection.
作者
刘爱红
朱雪琴
温涛
Liu Aihong;Zhu Xueqin;Wen Tao(Department of General Medicine,Punan Hospital,Pudong New District of Shanghai City,Shanghai 9200125,P.R.China)
出处
《老年医学与保健》
CAS
2022年第3期580-583,593,共5页
Geriatrics & Health Care
关键词
老年
心力衰竭
肺部感染
预后
影响因素
elderly
heart failure
pulmonary infection
prognosis
influence factor
