摘要
目的探讨疏血通联合替罗非班治疗脑梗死的临床疗效。方法选择2019年5月—2021年5月医院收治的脑梗死患者110例,分为观察组和对照组各55例。对照组予以疏血通治疗,观察组加用替罗非班治疗。观察两组临床疗效、中医证候积分、美国国立卫生院神经功能缺损(NIHSS)评分、日常生活能力(改良Barthel指数)评分、不良反应发生率、满意度。结果观察总有效率96.36%高于对照组的81.82%(P<0.01);与治疗前比较,两组治疗后NIHSS评分明显降低,观察组低于对照组(P<0.01);两组改良Barthel指数明显升高,观察组高于对照组(P<0.01);观察组不良反应率低于对照组(P<0.01);观察组总体满意度高于对照组(P<0.01)。结论疏血通联合替罗非班治疗脑梗死,可提高临床疗效,改善神经功能缺损症状,提升生活能力,减少不良反应,提高患者满意度,安全性高。
Objective To explore the effect of Shuxuetong combined with tirofiban in the treatment of cerebral infarction.Methods 110 patients with cerebral infarction treated in our hospital from May 2019 to may 2021 were selected for a prospective non randomized controlled study.The patients were treated with Shuxuetong alone(control group)and Shuxuetong combined with tirofiban(observation group).The curative effects of the two groups were observed,including the treatment effect,traditional Chinese medicine syndrome score,NIHSS score,daily living ability(modified Barthel Index)score and the incidence of adverse reactions after treatment Results The total effective rate of clinical treatment was significantly higher than that of the control group(P<0.01);compared with that before treatment,the NIHSS score of the two groups decreased significantly after treatment,and the NIHSS score of the observation group was significantly lower than that of the control group(P<0.01)The modified Barthel Index in the observation group was significantly higher than that in the control group(P<0.01),and the adverse reaction rate in the observation group was significantly lower than that in the control group(P<0.01)However,there were no serious adverse reactions in the two groups,and they were not given special treatment.They relieved themselves after drug withdrawal.The overall satisfaction of the observation group was higher than that of the control group(P<0.01).Conclusion Shuxuetong combined with tirofiban in the treatment of cerebral infarction can improve the clinical efficacy,improve the symptoms of neurological deficit,help to improve their living ability,reduce adverse reactions,improve patient satisfaction and promote their recovery as soon as possible.Compared with pure Shuxuetong,the combined drug treatment has better curative effect,higher safety and clinical application the value is high.
作者
陈慧杰
孙东东
胡洋
CHEN Huijie;SUN Dongdong;HU Yang(Kaifeng People's Hospital,Kaifeng 475000,Henan,China)
出处
《实用中医内科杂志》
2022年第3期136-138,共3页
Journal of Practical Traditional Chinese Internal Medicine
基金
开封市科技发展计划(2003066)。
关键词
疏血通
替罗非班
脑梗死
神经功能
生活能力
Shuxuetong
tirofiban
cerebral infarction
neurological function
ability to live
