摘要
目的探讨对老年患者给予右美托咪定复合丙泊酚实施辅助全麻后对其术后恶心呕吐及麻醉复苏产生的影响。方法选取2018年1月—2020年12月收治的80例老年气管插管全身麻醉患者进行麻醉研究。依据随机数字表法分为参照组(n=40,采用右美托咪定复合丙泊酚麻醉)以及研究组(n=40,采用丙泊酚麻醉);比较两组患者麻醉结果。结果研究组手术时间(77.63±5.29)min、麻醉时间(98.22±5.28)min、睁眼时间(7.23±1.25)min以及拔管时间(7.53±2.02)min均短于参照组,差异有统计学意义(t=10.170、8.776、10.687、10.327,P<0.05);T2~T7时,研究组MAP水平以及HR水平均低于参照组,差异有统计学意义(P<0.05);研究组心动过缓、术后呕吐、恶心、低血压并发症发生率均低于参照组,差异有统计学意义(χ^(2)=4.507、7.314、4.507、7.314,P<0.05);研究组躁动评分低于参照组,差异有统计学意义(P<0.05)。结论右美托咪定复合丙泊酚辅助全麻方式有效运用,可有效缩短老年患者手术时间、麻醉时间、睁眼时间以及拔管时间,显著降低血流动力学指标,并且术后恶心呕吐等并发症出现减少,改善麻醉复苏情况,促进老年气管插管全身麻醉患者总体预后水平提高。
Objective To investigate the effect of dexmedetomidine combined with propofol on postoperative nausea and vomiting and anesthesia resuscitation in elderly patients after adjuvant general anesthesia.Methods A total of 80 elderly patients with tracheal intubation and general anesthesia who were treated from January 2018 to December 2020 were selected for anesthesia research.According to the random number table method,they were divided into reference group(n=40,using dexmedetomidine combined with propofol anesthesia)and study group(n=40,using propofol anesthesia).The anesthesia results of the two groups of patients were compared.Results The operation time of the study group was(77.63±5.29)min,the anesthesia time was(98.22±5.28)min,the eye opening time was(7.23±1.25)min and the extubation time was(7.53±2.02)min,which were shorter than the reference group,the difference was statistically significant(t=10.170,8.776,10.687,10.327,P<0.05).From T2 to T7,the levels of MAP and HR in the study group were lower than those in the reference group,the difference was statistically significant(P<0.05).The incidences of bradycardia,postoperative vomiting,nausea,and hypotension in the study group were lower than those in the reference group,the difference was statistically significant(χ^(2)=4.507,7.314,4.507,7.314,P<0.05).The restlessness score of the study group was lower than that of the reference group,the difference was statistically significant(P<0.05).Conclusion Dexmedetomidine combined with propofol assisted by general anesthesia can effectively shorten the operation time,anesthesia time,eye opening time and extubation time in elderly patients.The hemodynamic indexes were significantly reduced,postoperative nausea and vomiting and other complications were reduced,and anesthesia resuscitation was improved,promoting the improvement of the overall prognosis of elderly patients with general anesthesia with endotracheal intubation.
作者
孙小珊
孔珉珉
SUN Xiaoshan;KONG Minmin(Department of Anesthesiology,the Second Affiliated Hospital of Shandong First Medical University,Tai'an,Shandong Province,271000 China)
出处
《系统医学》
2022年第6期59-62,共4页
Systems Medicine
关键词
右美托咪定
丙泊酚
全麻
老年患者
术后恶心呕吐
麻醉复苏
Dexmedetomidine
Propofol
General anesthesia
Elderly patients
Postoperative nausea and vomiting
Anesthesia resuscitation
