摘要
非稳态负荷(allostatic load,AL)主要与压力应激有关,而童年期逆境(adverse childhood experiences,ACEs)作为童年时期常见的应激源能对其产生严重且持久的影响。AL能够反映个体多个生理系统的综合磨损情况。该文主要综述了经历ACEs的个体对其AL各系统的影响和作用机制,以及ACEs的发生时间、亚型对AL的不同影响,为未来制定早期干预计划,减少不良结局的发生发展提供一定的理论基础。
Allostatic load(AL)is related to stress.Adverse childhood experiences(ACEs),as a common stress in childhood,can make a serious and lasting impact on it.Allostatic load can reflect the wear and tear of an individual’s physiological system.This article mainly reviews the functional changes of several systems of AL who have experienced ACEs,including neuroendocrine,metabolism,immune,and cardiovascular systems,as well as the different effects of the occurrence time and subtypes of ACES on AL,providing some theoretical basis for the development of early intervention plans in the future and reducing the occurrence and development of deleterious outcomes.
作者
贺云铃
王冬雪
任凯
李杨
张慧
HE Yunling;WANG Dongxue;REN Kai;LI Yang;ZHANG Hui(不详;Department of Nursing,Harbin Medical University,Harbin(150081),China)
出处
《中国学校卫生》
CAS
北大核心
2022年第3期472-475,共4页
Chinese Journal of School Health
基金
国家自然科学基金项目(71603064)。
关键词
生活变动事件
精神卫生
行为和行为机制
Life change events
Mental health
Behavior and behavior mechanisms
