摘要
目的探讨高分辨率核磁共振(HRMRI)在评估脑梗死患者斑块稳定性及成分中的应用价值。方法收集2019年6月~2021年6月我院行HRMRI的脑梗死与短暂性脑缺血发作(TIA)患者的临床病例资料共130例,将脑梗死患者作为观察组(n=72),TIA患者作为对照组(n=58)。比较两组患者动脉粥样硬化斑块位置、斑块稳定性、动脉斑块负荷参数、坏死脂质核心、斑块内出血、纤维帽破裂及管腔狭窄发生率。结果观察组斑块多集中于后壁(27.78%)及上壁(54.17%),对照组集中在前壁(43.10%)及下壁(34.49%);观察组不稳定性斑块的占比明显多于对照组(P<0.05);观察组管腔面积(LA)少于对照组(P<0.05),观察组管壁标准化指数(NWI)及血管重构指数(RI)多于对照组(P<0.05);观察组坏死脂质核心、斑块内出血及纤维帽破裂明显高于对照组(P<0.05)。结论高分辨率核磁共振可清晰呈现脑梗死患者血管斑块的影像学特征,客观准确鉴定斑块的稳定性及成分,对早期评估与诊断脑梗死有重要意义。
Objective To investigate the value of high-resolution magnetic resonance imaging(HRMRI)in assessing the stability and composition of plaque in patients with cerebral infarction.Methods A retrospective study analysis was adopted on patients with cerebral infarction and transient ischemic attack(TIA)who underwent HRMRI in the hospital.The clinical case data of 130 patients that met the criteria were collected between June 2019 and June 2021,and the patients with cerebral infarction were taken as observation group(n=72)and the patients with TIA were served as control group(n=58).The AS plaque location,plaque stability,arterial plaque load parameters and incidence rates of necrotic lipid core,intraplaque hemorrhage,fibrous cap rupture and lumen stenosis were compared between the two groups.Results The plaques in observation group were mostly concentrated on the posterior wall(20/72,27.78%)and superior wall(39/72,54.17%)while the plaques in control group were concentrated on the anterior wall(25/58,43.10%)and inferior wall(20/58,34.49%).The proportion of unstable plaques with(45/72,62.50%)in observation group was significantly higher than(14/58,24.14%)in control group.The lumen area(LA)in observation group was less than in control group while the normalized wall index(NWI)and vascular remodeling index(RI)were more than in control group.The incidence rates of necrotic lipid core,intraplaque hemorrhage and fibrous cap rupture were significantly higher than in control group.Conclusion HRMRI can clearly present the imaging features of vascular plaques in patients with cerebral infarction,and objectively and accurately identify the stability and composition of plaque.It is of great significance for early evaluation and diagnosis of cerebral infarction.
作者
吴经纬
吴水仙
陈斌
WU Jingwei;WU Shuixian;CHEN Bin(The Second Affiliated Hospital of Hainan Medical College,Haikou 570311,China)
出处
《西部医学》
2022年第4期600-604,共5页
Medical Journal of West China
基金
海南省医药卫生科研项目(18A200176)
海南省医药卫生科研项目(19A200131)。
关键词
高分辨率
核磁共振
脑梗死
斑块稳定性
High-resolution
MRI
Cerebral infarction
Plaque stability
