摘要
缺血性脑卒中具有高发病率、高致残率、高致死率、高复发率、高经济负担的特点,为患者家庭及社会带来沉重负担,静脉溶栓是急性缺血性脑卒中患者唯一被批准的全身再灌注治疗方式,是急性脑卒中管理的基石。然而,静脉溶栓后患者的获益情况因人而异,静脉溶栓后患者发生早期神经功能改善(ENI)是国内外研究者关注的热点,大量研究表明关于急性缺血性脑卒中静脉溶栓后发生ENI的因素各不相同。因此,临床医护人员早期识别和评估静脉溶栓后患者发生ENI的相关因素,对促进患者的转归具有重要意义。本文就急性缺血性脑卒中静脉溶栓后患者发生ENI的因素进行综述。
Ischemic stroke is characterized by high incidence,high disability,high mortality,high relapse rate,and high economic burden,which brings a heavy burden to patients’families and society.Intravenous thrombolysis(IVT)is the only approved s ystemic reperfusion therapy for patients with acute ischemic stroke(AIS)and the cornerstone of acute stroke management.However,the benefits of patients after IVT vary from person to person,and the occurrence of early neurological improvement(ENI)in patients treated by IVT is a hot topic for researchers both at home and abroad.A large number of studies have shown different factors regarding the occurrence of ENI after patients with AIS was treated by IVT.Therefore,early identification and assessment of factors associated with ENI in patients after IVT by clinical medical and nursing staff are important to facilitate the outcomes of patients.This paper reviews the factors associated with the occurrence of ENI in patients with AIS treated by IVT.
作者
杨琅晶
邹爱容
杨鸣春
YANG Langjing;ZOU Airong;YANG Mingchun(School of Nursing,Yunnan University of Chinese Medicine,Yunnan,Kunming 650504,China;Department of Internal Medicine,Yan'an Hospital Affiliated to Kunming Medical University,Yunnan,Kunming 650051,China)
出处
《中国医药科学》
2022年第5期44-47,121,共5页
China Medicine And Pharmacy
基金
云南省科技厅科技计划项目[2018FE001(-084)]。
关键词
急性缺血性脑卒中
静脉溶栓
早期神经功能改善
相关因素
Acute ischemic stroke
Intravenous thrombolysis
Early neurological improvement
Associated factors