摘要
目的探讨心电图T波改变、N末端脑钠肽前体(NT-proBNP)水平以及Gensini评分在评估心肌梗死患者冠状动脉(下称冠脉)病变严重程度中的价值。方法选择2019年12月至2020年12月宁波市医疗中心李惠利医院收治的心肌梗死患者100例,根据冠脉造影血管病变支数分为单支组(36例)、双支组(32例)、多支组(32例)。比较3组患者一般资料和心电图T波改变、NT-proBNP水平以及Gensini评分,分析冠脉病变支数与年龄、左心室射血分数、T波改变、NT-proBNP水平、Gensini评分的相关性。结果双支组患者年龄大于单支组,左心室射血分数低于单支组,多支组患者年龄大于双支组,左心室射血分数低于双支组,差异均有统计学意义(均P<0.05)。3组患者性别、吸烟史、饮酒史比较,差异均无统计学意义(均P>0.05)。双支组患者T波倒置患者占比、NT-proBNP水平、Gensini评分均高于单支组,多支组患者上述3项高于双支组,差异均有统计学意义(均P<0.05)。3组患者T波高尖比较,差异无统计学意义(P>0.05)。患者年龄、NT-proBNP水平、Gensini评分、T波倒置与冠脉多支病变呈正相关(r=0.833、1.561、0.965、0.655,均P<0.05),患者左心室射血分数与冠脉多支病变呈负相关(r=-1.052,P<0.01)。结论心肌梗死患者冠脉病变严重程度可用心电图T波、NT-proBNP、Gensini评分进行评估。
Objective To explore the application of ECG T wave changes,N-terminal pro-brain natriuretic peptide(NT-proBNP)level and Gensini score in evaluating the severity of coronary artery lesions in patients with myocardial infarction.Methods The clinical data of 100 patients with myocardial infarction admitted to Ningbo Medical Center Li Huili Hospital from December 2019 to December 2020 were retrospectively analyzed.According to the number of coronary artery lesions,they were divided into single-vessel lesions group(n=36),double-vessel lesions group(n=32),and multi-vessel lesions group(n=32).The basic data,ECG T wave changes,NT-proBNP levels,and Gensini scores were compared among the three groups,and the correlations of disease severity of coronary vessel lesions with age,left ventricular ejection fraction,T wave inversion,NT-proBNP level,and Gensini scores were analyzed.Results The age of double-vessel lesions group was significantly higher than that of single-vessel lesions group,and the left ventricular ejection fraction was significantly lower than that of single-vessel lesions group.The age of multi-vessel lesions group was significantly higher than that of double-vessel lesions group,and the left ventricular ejection fraction was significantly lower than that of double-vessel lesions group(P<0.05).There were no significant differences in gender,smoking history and drinking history among the three groups(P>0.05).The proportion of cases with T wave inversion,the NT-proBNP level,and Gensini score in double-vessel lesions group were significantly higher than those in single-vessel lesions group,while these indicators in multi-vessel lesions group were significantly higher than those in double-vessel lesions group(P<0.05),There was no significant difference in T wave peak among the three groups(P>0.05).The age of patients,NT-proBNP levle,Gensini score,T wave inversion were positively correlated with number of diseased coronary vessels(r=0.833,1.561,0.965,0.655,all P<0.05),while the left ventricular ejection fraction was negatively correlated with severity of coronary vessel lesions(r=-1.052,P<0.01).Conclusion The prognosis of patients with myocardial infarction can be determined by ECG T wave,NT-proBNP and Gensini scores,and NT-proBNP and Gensini scores are positively correlated with coronary multivessel disease.
作者
翁巧琳
王英
WENG Qiaolin;WANG Ying(ECG Unit,Ningbo Medical Center LiHuili Hospital,Ningbo 315040,China;不详)
出处
《浙江医学》
CAS
2022年第5期493-496,501,共5页
Zhejiang Medical Journal
关键词
心肌梗死
心电图
N末端脑钠肽前体
GENSINI评分
Myocardial infarction
Electrocardiogram
N-terminal pro-brain natriuretic peptide
Gensini score
