摘要
目的分析接受辅助生殖助孕多囊卵巢综合征(PCOS)晚期流产患者发生宫颈机能不全(CI)的影响因素。方法选取2019年1月至2020年12月郑州市妇幼保健院收治的辅助生殖助孕PCOS晚期流产患者102例,患者年龄(32.39±6.54)岁,单胎妊娠78例、多胎妊娠24例。按是否出现CI分为对照组(未出现CI)88例及观察组(出现CI)14例,比较两组患者一般情况,采用单因素分析(独立样本t检验、χ^(2)检验),差异有统计学意义的数据进行多因素logistic回归分析,筛查CI的影响因素。结果多因素logistic分析显示子宫平均径线、孕前体质量指数(BMI)、是否多胎及早产史为助孕晚期流产的PCOS患者出现CI的影响因素(OR=2.678、2.918、2.872、3.792,均P<0.05)。结论子宫平均径线、孕前BMI、是否多胎及早产史为助孕晚期流产的PCOS患者出现CI的影响因素,需针对以上因素采取相应的措施以降低出现CI的概率。
Objective To analyze the influencing factors of cervical insufficiency(CI)in patients with polycystic ovary syndrome(PCOS)complicated with late abortion who receive pregnancy-assisted therapy.Methods A total of 102 patients with PCOS with late abortion receiving pregnancy-assisted therapy were selected from Women&Infants Hospital of Zhengzhou between January 2019 and December 2020.The patients'age was(32.39±6.54)years old,and there were 78 cases of singleton pregnancy and 24 cases of multiple pregnancy.According to whether CI occurred,the patients were divided into a control group(without CI,88 cases)and an observation group(with CI,14 cases).The general conditions of the two groups were compared by univariate analysis(independent sample t test andχ^(2) test),multivariate logistic regression analysis was performed on the data with statistically significant differences in the univariate analysis to screen the influencing factors of CI.Results Multivariate logistic analysis showed that average uterine diameter,pre-pregnancy body mass index(BMI),multiple pregnancy,and preterm birth history were the influencing factors for CI in PCOS patients with late pregnancy-assisted abortion(OR=2.678,2.918,2.872,and 3.792;all P<0.05).Conclusions The average uterine diameter,pre-pregnancy BMI,multiple pregnancy,and preterm birth history are the influencing factors for CI in PCOS patients with late pregnancy-assisted abortion.It is necessary to take corresponding measures according to the above factors to reduce the probability of CI.
作者
刘彩霞
周新华
郭宝芝
郭欢欢
Liu Caixia;Zhou Xinhua;Guo Baozhi;Guo Huanhuan(Department of Gynecology,Women&Infants Hospital of Zhengzhou,Zhengzhou 450041,China)
出处
《国际医药卫生导报》
2022年第8期1077-1080,共4页
International Medicine and Health Guidance News
基金
2020年度河南省医学科技攻关计划项目(LHGJ20200751)。
