摘要
目的:探讨雷公藤多苷(GTW)的研究热点及趋势,为GTW的临床推广应用提供参考,为未来相关研究提供新的思路。方法:检索中国知网自建库至2021年6月7日GTW相关文献,运用CiteSpace软件对符合纳入标准的文献进行可视化分析。结果:最终纳入文献2322篇,最早始于1990年,核心作者有丁樱、李振彬、崔瑞琴、任献青、孙伟等;研究热点涉及糖尿病肾病、类风湿关节炎、子宫内膜异位症、银屑病、紫癜性肾炎、增效减毒、podocin、细胞因子、化学成分、炎症因子等;研究方法包括综述、系统评价/荟萃分析、实验研究、临床疗效观察、不良反应及安全性评价等。结论:对GTW的研究深入到多个医学学科,不良反应始终是研究的热点,团队之间的合作有待加强。
Objective:To explore the research hotspots and trends of tripterygium wilfordii glycosides(GTW)and provide references for the clinical application as well as new ideas for the future research of GTW. Methods:GTW-related literature was retrieved from CNKI covering the period of time from the building of the database to June 7, 2021, and CiteSpace software was used to conduct visualized analysis of the literature that met the inclusion criteria. Results:A total of 2322 pieces of literature since 1990 had been included, and the core authors included Ding Ying, Li Zhenbin, Cui Ruiqin, Ren Xianqing, Sun Wei, etc. Research focuses include diabetic nephropathy, rheumatoid arthritis, endometriosis, psoriasis, purpura nephritis, synergistic and attenuatory,podocin, cytokines, chemical components, inflammatory factors, etc. Research methods include review, systematic evaluation/meta-analysis, experimental study, clinical efficacy observation, adverse reactions, safety evaluation,etc. Conclusion:In-depth investigations on GTW have been carried out in many medical disciplines. Adverse reactions have always been the research focus of GTW, and the cooperation among research groups needs to be strengthened.
作者
吴静静
任献青
苏杭
孙宇莹
温盈盈
Wu Jingjing;Ren Xianqing;Su Hang;Sun Yuying;Wen Yingying(The First Affiliated Hospital to Henan University of Chinese Medicine,Zhengzhou 450000,China;School of Pediatrics,Henan University of Chinese Medicine,Zhengzhou 450046,China)
出处
《中国药事》
CAS
2022年第2期170-178,共9页
Chinese Pharmaceutical Affairs
基金
国家自然科学基金联合项目(编号U200410252)
河南省中医药拔尖人才培养项目(编号豫中医科教[2018]5号)。
