摘要
目的系统评价森林疗养对抑郁情绪的作用。方法运用计算机检索PubMed、Cochrane library、EMbase、Web of science、CNKI、万方数据库、SinoMed收集森林疗养对抑郁情绪作用的随机对照试验(randomized controlled trial,RCT)数据,检索时间范围为各数据库建库至2020年8月。提取相关资料并按照Cochrane系统评价员手册5.1.0评价质量后,采用RevMan 5.3软件对数据进行Meta分析。结果共纳入10项研究,合计489例受试者。Meta分析结果显示,试验组心境状态量表评分显著优于对照组,差异有统计学意义(MD=1.24,95%CI1.10~1.39,P<0.00001)。在汉密尔顿抑郁量表、皮质醇水平和肾上腺素水平上试验组和对照组差异有统计学意义[分别为(MD=-5.50,95%CI-6.58~-4.42,P<0.00001),(MD=-39.08,95%CI-63.85~-14.30,P=0.002)和(MD=-38.21,95%CI-48.48~-27.94,P<0.00001)]。贝克抑郁量表、医院焦虑与抑郁量表、睾酮水平、活性氧代谢物水平和生物抗氧化能力试验组和对照组差异无统计学意义(P>0.05)。结论森林疗养是一种新兴的和有效的抑郁情绪干预手段。然而,所纳入的研究缺乏方法的严谨性。未来在研究评估森林疗养对抑郁情绪的作用方面需要严格的试验设计。
Objective To investigate effects of forest therapy on depressive mood.Methods PubMed,Cochrane library,EMbase,Web of science,CNKI,Wanfang databases,SinoMed were electronically searched to collect rando-mized controlled trial(RCT)involving the effect of forest therapy on depressive mood from inception to August,2020.Relevant information was extracted,and the quality was evaluated according to the Cochrane Handbook for Systematic Reviews of Interventions 5.1.0.Meta-analysis was performed using RevMan 5.3 software.Results Ten RCTs involving 489 subjects were included.The results of Meta-analysis showed that Profile of Mood States score of experimental group was significantly better than that of control group(MD=1.24,95%CI:1.10~1.39,P<0.0001).For Hamilton Depression Rating Scale,cortisol and epinephrine level,the difference between the experimental group and the control group was statistically significant[(MD=-5.50,95%CI:-6.58~-4.42,P<0.0001),(MD=-39.08,95%CI:-63.85~-14.30,P=0.002)and(MD=-38.21,95%CI:-48.48~-27.94,P<0.0001)],respectively.For Beck Depression Inventory,Hospital Anxiety and Depression Scale,and testosterone level as well as reactive oxygen metabolites and biological antioxidant potentials,there was no significant difference between the two groups(P>0.05).Conclusion Forest therapy is an emerging and effective intervention for depressive mood.However,the included studies lacked methodological rigor.Future studies assessing the effect of forest therapy on depression mood using rigorous study designs are needed.
作者
赵珊珊
李怡文
常晓红
刘阳
南海龙
ZHAO Shanshan;LI Yiwen;CHANG Xiaohong;LIU Yang;NAN Hailong(Clinical Trial Institution/Department of Pharmacy,Emergency General Hospital,Beijing,100028,China;不详)
出处
《中国社会医学杂志》
2022年第1期97-102,共6页
Chinese Journal of Social Medicine
基金
中央级公益性科研院所基本科研业务费专项基金项目(CAFYBB2019ZC008)
国家应急管理部应急总医院医学发展科研基金(K201816)。
