摘要
目的探讨妊娠期糖尿病患者血糖控制治疗中使用胰岛素皮下注射治疗的价值。方法纳入2016年1月—2020年4月90例妊娠期糖尿病患者研究为研究对象,按双盲法分为对照组(n=45,采用饮食和运动疗法)、观察组(n=45,在对照组基础上皮下注射胰岛素),统计两组临床疗效、不良妊娠结局、临床指标、新生儿不良事件发生率。结果观察组临床疗效(95.56%)高于对照组(80.00%),差异有统计学意义(P<0.05)。观察组不良妊娠结局(13.33%)低于对照组(40.00%),差异有统计学意义(P<0.05)。治疗前,两组FPG、2 hPG、HbA1c对比差异无统计学意义(P>0.05),治疗后观察组FPG、2 hPG、HbA1c低于对照组,血糖达标时间短于对照组,差异有统计学意义(t=6.974、5.927、8.287、4.627,P<0.05)。观察组新生儿不良事件发生率(8.89%)低于对照组(28.89%),差异有统计学意义(P<0.05)。结论选择胰岛素皮下注射对妊娠期糖尿病进行治疗有效性较高,值得借鉴及参考。
Objective To explore the value of insulin subcutaneous injection in the treatment of blood glucose control in patients with gestational diabetes.Methods A study of 90 patients with gestational diabetes from January 2016 to April 2020 was included as the research object.According to the double-blind method,they were divided into a control group(n=45,using diet and exercise therapy)and an observation group(n=45,subcutaneous injection of insulin on the basis of the control group).The clinical efficacy,adverse pregnancy outcomes,clinical indicators,and incidence of adverse neonatal events in the two groups were counted.Results The clinical efficacy of the observation group(95.56%)was higher than that of the control group(80.00%),and the difference was statistically significant(P<0.05).The adverse pregnancy outcome of the observation group(13.33%)was lower than that of the control group(40.00%),and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in FPG,2 hPG,HbA1c between the two groups(P>0.05).After treatment,the observation group had FPG,2 hPG,HbA1c,lower than the control group,the time to reach the target blood glucose was shorter than that of the control group,and the difference was statistically significant(t=6.974,5.927,8.287,4.627,P<0.05).The incidence of neonatal adverse events in the observation group(8.89%)was lower than that in the control group(28.89%),and the difference was statistically significant(P<0.05).Conclusion It is more effective to choose insulin subcutaneous injection for the treatment of gestational diabetes,which is worthy of reference and reference.
作者
陈桂芳
CHEN Guifang(Department of Obstetrics,Maternity and Child Health Hospital of Xinghua City,Xinghua,Jiangsu Province,225700 China)
出处
《糖尿病新世界》
2021年第24期80-82,86,共4页
Diabetes New World Magazine
关键词
胰岛素
皮下注射
妊娠期糖尿病
血糖控制效果
妊娠结局
Insulin
Subcutaneous injection
Gestational diabetes
Blood glucose control effect
Pregnancy outcome
