摘要
目的:通过分析中医药治疗扩张型心肌病(DCM)的临床文献及名医医案,探讨DCM的中医证治规律。方法:通过检索中国期刊全文数据库、中国学术期刊数据库、中国期刊数据库、PubMed等国内外大型数据库收录的有关中医药治疗DCM的文献及名医医案,并查阅河南中医药大学及南阳医学高等专科学校图书馆内有关DCM诊治纸质材料,提取文献和医案中临床症状、辨证分型、用药情况等信息,建立数据库,分析DCM的中医证候分布和治疗方药规律。结果:共筛选到152篇文献及195篇医案,其中胸闷、心悸、乏力等是患者最常见的症状,舌淡红、舌暗红、薄白苔,脉细、脉沉是最常见的舌象及脉象。发现与DCM相关的病性因素10个,以气虚、血瘀为主;病位因素6个,以心、肾为主。共发现临床证候62种,以气虚血瘀、气阴两虚、水湿停滞、血瘀水停、心肾阳虚和痰瘀互结证最常见。涉及中药共计291味,用药频次≥50次的药物有48味,黄芪是使用最多药物。结论:DCM病性虚实夹杂,主要病位以心肾为主,临床以气虚血瘀证、气阴两虚证最为常见,临床治疗以补虚、活血、利水等药物为主。
Objective:To explore the law of TCM syndrome and treatment of dilated cardiomyopathy(DCM)by analyzing the clinical literatures and famous medical records of traditional Chinese medicine.Methods:By searching the literatures and famous medical records on the treatment of DCM by traditional Chinese medicine included in large databases at home and abroad,such as Chinese Journal Full-text Database,Chinese academic journal database,Chinese Journal Database and PubMed,and consulting the paper materials on the diagnosis and treatment of DCM in the libraries of Henan University of traditional Chinese medicine and Nanyang Medical College.Extract the information of clinical symptoms,syndrome differentiation and medication in literatures and medical records.Establish a database to analyze the distribution of TCM syndromes and the law of therapeutic prescriptions of DCM.Results:A total of 152 literatures and 195 medical cases were screened.Chest tightness,palpitation and fatigue were the most common symptoms.Light red tongue,dark red tongue,thin white fur,thin pulse and heavy pulse were the most common tongue and pulse.It was found that there were 10 pathogenic factors related to DCM,mainly Qi deficiency and blood stasis.There are 6 location factors,mainly heart and kidney.A total of 62 clinical syndromes were found,of which qi deficiency and blood stasis,qi and yin deficiency,water dampness stagnation,blood stasis and water stagnation,heart and kidney yang deficiency and phlegm and blood stasis were the most common.A total of 291 traditional Chinese medicines were involved,and 48 medicines were used more than 50 times.Astragalus was the most used medicine.Conclusion:DCM is mixed with deficiency and excess,and the main disease location is heart and kidney.Qi deficiency and blood stasis syndrome and qi yin deficiency syndrome are the most common in clinic.The clinical treatment is mainly based on drugs such as tonifying deficiency,promoting blood circulation and diuresis.
作者
张会超
王振涛
韩丽华
王灿灿
贺喜盈
边汝涛
ZHANG Huichao;WANG Zhentao;HAN Lihua;WANG Cancan;HE Xiying;BIAN Rutao
出处
《新中医》
CAS
2021年第23期13-17,共5页
New Chinese Medicine
基金
河南省中医管理局国家中医临床研究基地科研专项(2019JDZX005)
河南省中医药拔尖人才培养项目(豫卫中医函[2021]15号)。
关键词
扩张型心肌病
中医证候
文献研究
用药规律
Dilated cardiomyopathy
TCM syndrome
Literature study
Medication law
