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分化型甲状腺癌患者在放射性^(131)I治疗期间采用心理护理及行为干预的临床价值分析 被引量:19

The Clinical Value of Psychological Nursing Care and Behavioral Intervention in Patients with Differentiated Thyroid Cancer During Radioactive ^(131)I Therapy
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摘要 目的探讨DTC患者在RAI治疗期间采用心理护理及行为干预的临床价值。方法选取我院核医学科2018年1月至2018年12月接受RAI治疗的DTC患者98例作为研究对象,随机分为对照组(n=49)和实验组(n=49),对照组实施常规治疗护理,实验组在对照组的基础上实施心理护理及行为干预。在RAI治疗前1 d、RAI治疗后1周、RAI治疗后3月等3个时间点对患者的心理、生理健康状态进行调查,通过比较两组受试者的甲状腺功能、生存质量评分、焦虑指数、抑郁指数和护理满意度的发展演变情况,评估心理护理及行为干预的临床价值。结果对照组和实验组受试者除RAI治疗前1d、治疗后1周时的TSH差异存在统计学意义外,TT_(3)、TT_(4)、FT_(3)、FT_(4)、TSH在各时间点差异均无统计学意义(P>0.05)。RAI治疗前1d,对照组和实验组受试者的生存质量评分分别为72.25±6.47和70.15±6.01,焦虑评分分别为25.63±3.21和27.26±4.36,抑郁评分分别为25.26±4.59和24.23±3.94,差异均无统计学意义(P>0.05);RAI治疗后1周,对照组和实验组受试者的生存质量评分分别为80.25±4.36和68.36±3.21,焦虑评分分别为28.37±3.69和23.54±2.59,抑郁评分分别为27.95±5.75和20.67±4.91,差异均存在统计学意义(P<0.001);RAI治疗3月后,对照组和实验组受试者的生存质量评分分别为69.51±5.98和40.17±4.59,焦虑评分分别为18.19±5.26和11.32±2.61,抑郁评分分别为19.54±5.78和9.51±2.31,差异均存在统计学意义(P<0.001)。对照组和实验组受试者的护理满意度分别为65.31%和87.76%,差异存在统计学意义(P<0.001)。两组受试者的甲状腺切除相关症状在三个时间点差异均无统计学意义(P>0.05)。结论DTC手术后患者在RAI治疗期间采取心理护理及行为干预能够有效缓解患者焦虑、抑郁等负面情绪,提高患者生活质量,但对甲功无明显影响。 Objective To explore the clinical value of psychological nursing and behavioral intervention in patients with DTC during RAI treatment.Methods 98 patients with DTC who were treated with RAI in the Department of Nuclear Medicine of our hospital from January,2018 to December,2018 were randomly divided into the control group(n=49)and experimental group(n=49).The control group received routine treatment and nursing care,and the experimental group received psychological nursing care and behavioral intervention in addition.The psychological and physical health status of these patients were investigated at three time points:1 day before RAI treatment,1 week after RAI treatment and 3 months after RAI treatment.The clinical value of psychological nursing care and behavioral intervention were evaluated by comparing the quality of life,thyroidectomy-related symptom scores,RAI treatment-related symptom scores,anxiety index,depression index and nursing satisfaction between the two groups.Results Except for TSH in 1 day before RAI treatment and 1 week after treatment,there was no significant difference in TT_(3),TT_(4),FT_(3),and FT_(4) between the control group and experimental group(P>0.05).1 day before RAI treatment,the scores of the quality of life between the control group and experimental group were 72.25±6.47 and 70.15±6.01,the anxiety index were 25.63±3.21 and 27.26±4.36,and the depression index were 27.95±5.75 and 20.67±4.91,which showed no significant difference(P>0.05).1 week after RAI treatment,the scores of quality of life between the two groups were 80.25±4.36 and 68.36±3.21,the anxiety index were 28.37±3.69 and 23.54±2.59,the depression index were 27.95±5.75 and 20.67±4.91,which showed significant differences(P<0.001).3 months after RAI treatment,the scores of the quality of life,anxiety,depression in the control group and the experimental group were 69.51±5.98 and 40.17±4.59,18.19±5.26 and 11.32±2.61,19.54±5.78 and 9.51±2.31,respectively,which showed significant differences(P<0.001).The nursing satisfaction degree in the control group and the experimental group were 65.31%and 87.76%respectively,which showed significant differences(P<0.001).There was no significant difference in thyroidectomy-related symptoms between the two groups at three time points(P<0.05).The symptoms related to RAI treatment in the two groups were aggravated at 1 week after RAI treatment and relieved at 3 months after RAI,but there was no significant difference between the two groups(P<0.05).Conclusion Psychological nursing care and behavioral intervention during the treatment of RAI in patients with DTC after operation can effectively relieve the negative emotions such as anxiety and depression and improve the quality of life,but has no significant effect on thyroid function.
作者 贺瑞洁 汪静 王喜青 HE Ruijie;WANG Jing;WANG Xiqing(Department of Nuclear Medicine,The First Affiliated Hospital(Xijing Hospital)of Air Force Medical University,Xi’an 710000,China)
出处 《标记免疫分析与临床》 CAS 2021年第12期2011-2016,2028,共7页 Labeled Immunoassays and Clinical Medicine
基金 国家自然科学基金青年项目(编号:81801730)。
关键词 分化型甲状腺癌 放射性^(131)I治疗 心理护理 生活质量 Differentiated thyroid carcinoma Radioactive^(131)I therapy Psychological nursing Quality of life
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