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抑郁症患者童年创伤与临床特征的相关性分析 被引量:5

Correlation Analysis of Childhood Trauma and Clinical Characteristics in Patients with Major Depression
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摘要 目的童年创伤是抑郁症最重要的易患风险因子之一,但其与抑郁症症状之间的关系仍不完全清楚。本研究旨在探究童年创伤与抑郁症临床特征之间的相关性。方法招募了54名符合ICD-10抑郁发作诊断标准的抑郁症患者,并使用童年创伤问卷评定抑郁症患者童年创伤的情况。结果超过75.00%的抑郁症患者伴有至少一种类型的童年创伤,其焦虑症状(U=381.50,P=0.07);情感虐待(r=0.39,P=0.004)、躯体虐待(r=0.307,P=0.024)都与抑郁症严重程度相关;同时情感虐待(r=0.451,P=0.001)、躯体虐待(r=0.305,P=0.025)、躯体忽视(r=0.334,P=0.014)、总虐待(r=0.379,P=0.005)都与焦虑症状程度相关;情感虐待与更严重的认知障碍(r=0.352,P=0.009)、绝望感(r=0.326,P=0.016)、更早的发病年龄(r=-0.432,P=0.001)相关;此外,自杀(F=5.031,P=0.004)与自卑感(F=3.714,P=0.01)更突出的抑郁症患者童年时期经历了更多的情感虐待。结论伴有童年创伤的抑郁症患者具有更严重的抑郁症状及焦虑症状,童年情感虐待创伤经历使抑郁症患者发病年龄更早,并更可能表现有认知障碍、绝望感、自杀及自卑感。 Objective Childhood trauma is one of the most important risk factors for depression, and its relationship with depressive symptoms has not been clarified. The purpose of this study was to analyze the correlation between childhood trauma and depressive symptoms. Methods Fifty-four patients with depression who met the ICD-10 criteria for depressive episode were recruited and the childhood trauma questionnaire was used to assess the status of childhood trauma. Results More than 75.00% of patients with depression were associated with at least one type of childhood trauma, and they had more anxiety symptoms(U=381.50, P=0.07). Emotional abuse(r=0.39, P=0.004) and physical abuse(r=0.307, P=0.024) were associated with more severe depression. Emotional abuse(r = 0.451, P = 0.001), physical abuse(r = 0.305, P = 0.025), physical neglect(r = 0.334, P= 0.014), total abuse(r = 0.379, P= 0.005) were associated with greater anxiety symptoms. Emotional abuse was associated with more severe cognitive impairment(r = 0.352, P= 0.009), feeling of despair(r = 0.326, P= 0.016) and earlier age of onset(r =-0.432, P = 0.001). In addition, depressed patients with higher levels of suicide(F = 5.031, P = 0.004) and inferiority complex(F = 3.714, P = 0.01) experienced more emotional abuse in childhood. Conclusions Our data indicate that emotional abuse may be most closely related to the characteristics of major depression. Early prevention or intervention of emotional abuse during childhood and adolescence may be effective in reducing the onset and development of depressive symptoms. At the same time, depression patients who suffered severe emotional abuse in childhood, suicide prevention should be done in advance, and targeted emotional support should be given to their inferiority complex, despair and other negative cognition.
作者 罗显梅 方泽漫 林凌云 黄庆军 张瀚迪 LUO Xian-mei;FANG Ze-man;LIN Ling-yun;HUANG Qing-jun;ZHANG Han-di(Shantou University Mental Health Center,Shantou 515041,China;The Fourth People's Hospital of Chengdu,Chengdu 610000,China)
出处 《伤害医学(电子版)》 2021年第3期20-26,共7页 Injury Medicine(Electronic Edition)
基金 广东省医学科学技术研究基金(A2020450)。
关键词 童年创伤 抑郁症 情感虐待 自杀 自卑感 childhood trauma depression emotional abuse suicide inferiority complex
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