摘要
目的探究MR引导下射频消融治疗乏血供原发性肝癌的有效性及安全性。方法选取对我院2018年2月~2019年2月收治的80例乏血供原发性肝癌患者展开对照分析,将其分为观察组(MR引导下射频消融治疗)与对照组(手术治疗)各40例,分组方法为随机数字表法,探讨实施不同治疗对治疗效果的影响。结果治疗前两组在总胆红素(TBIL)、谷丙转氨酶(ALT)、谷草转氨酶(AST)、肝功能及甲胎蛋白(AFP)、癌胚抗原(CEA)差异无统计学意义(P>0.05),治疗后两组TBIL、ALT、AST、AFP和CEA均显著低于治疗前(P<0.05),但两组TBIL、ALT、AST、AFP和CEA比较差异无统计学意义(P>0.05),两组在癌灶转移率、术后1年生存率差异无统计学意义(P>0.05),观察组在住院时间、住院费用显著比对照组低(P<0.05),两组在术后并发症发生率进行对比,观察组(7.50%)显著比对照组(67.50%)低(P<0.05)。结论对乏血供原发性肝癌采用MR引导下射频消融治疗后,疗效显著,对肝功能及AFP、CEA的改善及癌灶转移率、术后1年生存率与手术治疗接近,且住院时间更短,住院费用更低,且术后并发症发生率更低,安全性更高,此方法值得应用与推广。
Objective To explore the efficacy and safety of MR-guided radiofrequency ablation in the treatment of primary liver cancer.Methods A comparative study was carried out on 80 cases of primary liver cancer with lack of blood supply admitted to our hospital from February 2018 to February 2019.They were divided into observation group(radiofrequency ablation under MR guidance)and control group(surgical treatment),with 40 cases in each.The grouping method was random digital table,and the effect of different treatments on the therapeutic effect was discussed.Results Before treatment,there was no significant difference in total bilirubin(TBIL),alanine aminotransferase(ALT),aspartate aminotransferase(AST),liver function,alpha fetoprotein(AFP),carcinoembryonic antigen(CEA)(P>0.05).There was no significant difference in TBIL,ALT,AST,AFP and CEA between the two groups(P>0.05).There was no significant difference in tumor metastasis rate and 1-year survival rate(P>0.05).The length of stay and cost of stay in the observation group were significantly lower than those in the control group(P<0.05).The incidence of postoperative complications in the observation group(7.50%)was significantly lower than that in the control group(67.50%)(P<0.05).Conclusion After MR guided radiofrequency ablation for primary liver cancer with poor blood supply,the curative effect is significant.The improvement of liver function,AFP,CEA,metastasis rate of cancer focus and 1-year survival rate after operation are close to that of operation.The time of hospitalization is shorter,the cost of hospitalization is lower,and the incidence of postoperative complications is lower,and the safety is higher.This method is worthy of application and promotion.
作者
黄钦熊
谭理连
陶江涛
HUANG Qinxiong;TAN Lilian;TAO Jiangtao(Guangzhou Medical University,Guangzhou 511436,P.R.China;Department of Radiology,Shenzhen People's Hospital,Shenzhen 518000,P.R.China;Department of Radiology,The Second Affiliated Hospital of Guangzhou Medical University,Guangzhou 510260,P.R.China;Department of General Surgery,Shenzhen People's Hospital,Shenzhen 518000,P.R.China)
出处
《医学影像学杂志》
2021年第7期1204-1207,共4页
Journal of Medical Imaging
关键词
原发性肝癌
乏血供
射频消融
磁共振成像
引导
疗效
介入性
放射学
Primary liver cancer
Lack of blood supply
Radiofrequency ablation
Magnetic resonance imaging
Guidance
Efficacy
Interventional
Radiology
