摘要
目的采用高分辨率MRI探讨颈动脉血管重构与脑缺血症状之间的关系,为颈动脉粥样硬化患者提供分层依据。资料与方法回顾性分析71例颈动脉粥样硬化患者的临床及颈动脉高分辨率MRI资料。按照诊断标准将患者分为缺血性脑卒中组和非卒中组,计算两组患者颈动脉斑块的管壁厚度、管腔面积、血管面积、重构指数(RI)、偏心指数(EI)、管壁标准化指数(NWI),分析斑块负荷特征与缺血性脑卒中的关系。结果缺血性脑卒中组患者颈总动脉与颈内动脉RI分别为2.11±0.65和1.91±0.34,均高于非卒中组的1.07±0.53、1.22±0.47;颈总动脉与颈内动脉的管壁厚度分别为(2.35±0.33)mm和(1.83±0.98)mm,均大于非卒中组的(1.96±0.41)mm、(1.01±0.75)mm,差异均有统计学意义(P<0.05)。缺血性脑卒中组患者颈总动脉NWI大于非卒中组,差异有统计学意义(0.46±0.12比0.39±0.08,P<0.05)。两组患者EI差异无统计学意义(P>0.05)。结论正性重构、血管壁厚度与患者缺血性症状有关,可作为评价颈动脉易损斑块的潜在危险因子,用于改善心血管风险分层。
Purpose To investigate the association between carotid artery remodeling and symptoms of ischemic stroke via high-resolution MRI,providing hierarchical basis for patients with atherosclerosis.Materials and Methods Seventy-one patients who underwent carotid high-resolution MRI were retrospectively collected and analyzed,all patients were divided into ischemic stroke group and asymptomatic group.Wall thickness,vessel area,lumen area,remodeling index(RI),eccentricity index(EI),and normalized wall index(NWI)were calculated and analyzed,presenting the relationship between plaque characteristics and ischemic stroke.Results RI of common carotid artery and internal carotid artery in the ischemic stroke group was 2.11±0.65 and 1.91±0.34,respectively,which was significantly higher than that of the asymptomatic group(1.07±0.53 and 1.22±0.47,respectively).Wall thickness of common carotid artery and internal carotid artery in the ischemic stroke group was(2.35±0.33)mm and(1.83±0.98)mm,respectively,which was significantly higher than that of the asymptomatic group[(1.96±0.41)mm and(1.01±0.75)mm,P<0.05].The NWI of the common carotid artery was significantly higher than that of the asymptomatic group(0.46±0.12 vs.0.39±0.08,P<0.05).There was no significant difference in EI between the ischemic stroke group and the asymptomatic group(P>0.05).Conclusion Positive arterial remodeling and wall thickness are significantly associated with ischemic symptoms,evaluating potential risk factors in carotid artery vulnerable plaques and improving the classification of cardiovascular risk.
作者
李文玲
马丽
王志涛
田兴仓
张露露
朱力
LI Wenling;MA Li;WANG Zhitao;TIAN Xingcang;ZHANG Lulu;ZHU Li(Department of Radiology,General Hospital of Ningxia Medical University,Yinchuan 750000,China;不详)
出处
《中国医学影像学杂志》
CSCD
北大核心
2021年第5期444-448,共5页
Chinese Journal of Medical Imaging
基金
宁夏医科大学校级科研项目(XM2016039)
宁夏高等学校一流学科建设(宁夏医科大学国内一流建设学科临床医学)资助项目(NXYLXK2017A05)。
关键词
卒中
动脉粥样硬化
颈动脉疾病
磁共振成像
血管重构
Stroke
Atherosclerosis
Carotid artery diseases
Magnetic resonance imaging
Arterial remodeling
