摘要
目的通过分析1例中枢神经系统曼氏裂头蚴感染病例,探讨中枢神经系统曼氏裂头蚴感染的临床特点、病理学特征、诊断及鉴别诊断。方法患者男性,52岁,腰腿痛10年,加重1年,以脊髓占位性病变收入院,入院后行“髓内占位切除术”。回顾性分析该例中枢神经系统曼氏裂头蚴感染病例的临床表现、病理学特征、免疫组化和特染结果,并进行相关文献复习。结果术后病理(髓内病变)见少许神经胶质,可见大量淋巴细胞、浆细胞及嗜酸性粒细胞浸润,部分区域肉芽肿形成,见隧道样坏死;查见虫体,其内可见钙化及石灰小体形成等典型曼氏裂头蚴感染特征。结论中枢神经系统曼氏裂头蚴感染是一种发生于中枢神经系统的少见病变,诊断困难,该例患者诊治历时10年余,最终术后病理得以明确诊断。
Objective To investigate the clinical,pathological,diagnosis and differential diagnosis of central nervous system sparganosis mansoni infection by analyzing a case of central nervous system sparganosis mansoni infection.Methods The patient was male,52 years old,with 10 years of lumbago and leg pain,and one year of aggravation.The patient was admitted to hospital with spinal cord occupying lesions and was treated with“intramedullary space occupying resection”.The clinical manifestations,pathological features,immunohistochemical and specific staining results of this case were analyzed retrospectively,and the related literature review was conducted.Results Postoperative pathology(intramedullary lesions)showed a small amount of neuroglia,infiltration of a large number of lymphocytes,plasma cells and eosinophils,formation of granuloma in some areas,and tunnel like necrosis,typical infection characteristics of sparganosis mansoni,such as calcification and formation of calcareous bodies,were also observed.Conclusion Central nervous system sparganosis mansoni infection is a rare disease in the central nervous system,which is difficult to diagnose.The diagnosis and treatment of this patient lasted for more than 10 years,and the final postoperative pathology has been confirmed.
作者
杨江辉
李博文
高国强
雒文英
张晓慧
刘浩
李勇
于燕
尹洪芳
YANG Jianghui;LI Bowen;GAO Guoqiang;LUO Wenying;ZHANG Xiaohui;LIU Hao;LI Yong;YU Yan;YIN Hongfang(Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing 102218, China)
出处
《标记免疫分析与临床》
CAS
2021年第5期779-781,共3页
Labeled Immunoassays and Clinical Medicine
关键词
中枢神经系统
曼氏裂头蚴
感染
病理诊断
鉴别诊断
Central nervous system
Sparganum mansoni
Infection
Pathological diagnosis
Differential diagnosis
