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Novel deletion mutations of the PIH1D3 gene in an infertile young man with primary ciliary dyskinesia and his cousin with Kartagener’s syndrome 被引量:1

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摘要 Dear Editor,Male infertility is defined as the inability to achieve pregnancy in a fertile female partner even after 12 months of unprotected intercourse.In humans,it accounts for 40%-50%of cases of infertility,1 and it occurs most often due to problems with sperm production or sperm delivery.Male infertility is commonly due to deficiencies in semen,and semen quality is used as a surrogate measure of male fecundity.Primary ciliary dyskinesia(PCD)is a rare cause of male infertility.2,3 It is an autosomal recessive genetic condition that causes abnormal function of cilia.Cilia are microscopic finger-like projections on the surface of the cells.
出处 《Asian Journal of Andrology》 SCIE CAS CSCD 2021年第3期330-332,共3页 亚洲男性学杂志(英文版)
基金 the National Key R&D Program of China(No.2017YFC1002003) the China Postdoctoral Science Foundation(No.2019M661521).
关键词 PARTNER protected CILIA
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