摘要
This study is to report a ZnSe quantum dot with a large two-photon absorption cross section and good biocompatibility,which can be used in bioimaging.Fluorescence emission at 410 nm is observed in the quantum dot under 760-nm laser excitation.These biocompatible quantum dots exhibit a two-photon cross-section of 9.1×105 GM(1 GM=10-50 cm4·s/photon).Two-photon excited laser scanning microscopic images show that cells co-cultured with ZnSe quantum dots are found in the blue channel at a fluorescence intensity that is 14.5 times that of control cells not cocultured with quantum dots.After incubating zebrafish larvae with ZnSe quantum dots for 24 h,the fluorescence intensity of the yolk sac stimulated by ultraviolet light is 2.9 times that of the control group.The proposed material shows a great potential application in biological imaging.
作者
Nan-Nan Zhang
Li-Ya Zhou
Xiao Liu
Zhong-Chao Wei
Hai-Ying Liu
Sheng Lan
Zhao Meng
Hai-Hua Fan
张楠楠;周立亚;刘潇;韦中超;刘海英;兰胜;孟钊;范海华(Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and Devices,School of Information and Optoelectronic Science and Engineering,South China Normal University,Guangzhou 510006,China;School of Chemistry and Chemical Engineering,Guangxi University,Nanning 530004,China;Guangdong Women and Children Hospital,Guangzhou 510000,China)
基金
Project supported by the National Natural Science Foundation of China(Grant Nos.61774062 and U20A20206)
the Science and Techology Program of Guangzhou City,China(Grant No.2019050001)
the Natural Science Foundation of Guangdong Province,China(Grant Nos.2018A030313854 and2016A030308010)。
