摘要
糖尿病(diabetes mellitus,DM)是以高血糖为特征的代谢性疾病。糖尿病时长期存在的高血糖,导致各种组织,特别是眼、肾、心脏、血管、神经的慢性损害、功能障碍,这些并发症的发生常威胁着患者的生命。因此,迫切需要安全有效的药物来干预糖尿病并发症。黄芪是常见的补益中药,是众多抗糖尿病中药复方的关键组成之一,黄芪富含多糖(APS)、皂苷(ASS)、黄酮(ASF)等抗糖尿病成分,对糖尿病并发症有较好的作用。本文就近些年黄芪干预糖尿病并发症及作用机制进行文献进行综述,为黄芪干预糖尿病并发症研究提供参考。
Diabetes mellitus is a metabolic disease that is characterized by high blood sugar levels.Chronic hyperglycemia in diabetes leads to chronic damage and dysfunction of various tissues,especially the eyes,kidneys,heart,blood vessels,and nerves.These complications often threaten the life of patients.Therefore,there is an urgent requirement for safe and effective drugs to intervene in diabetic complications.Astragali radix is a common tonic in Chinese medicine and one of the main components of many anti-diabetes treatments using Chinese herbal compounds.Astragali radix is rich in polysaccharides(APS),saponins(ASS),flavones(ASF),and other anti-diabetes components,which have a good effect on the complications of diabetes.In this article,literature on the complications and mechanism of Astragali radix for intervention in diabetes in recent years is reviewed to provide a reference for future studies on complications of intervention by Astragali radix in diabetes.
作者
刁元元
李玉梅
李晓文
王楚盈
DIAO Yuanyuan;LI Yumei;LI Xiaowen;WANG Chuying(Changchun University of Traditional Chinese Medicine,Pharmacy College,Changchun 130117,China)
出处
《中国比较医学杂志》
CAS
北大核心
2021年第4期123-128,共6页
Chinese Journal of Comparative Medicine
基金
国家自然基金项目(81173597)
吉林省卫生计生青年科研课题(2014Q046)
吉林省教育厅“十三五”科学技术项目(JJKH20190455KJ)
吉林省卫生计生青年科技骨干培养计划项目(2016Q052)
吉林省中医药科技项目(2017005)
长春中医药大学“杏林学者工程”青年科学家计划项目。
关键词
黄芪
糖尿病神经病变
糖尿病心肌病
糖尿病肾病
糖尿病视网膜病变
糖尿病足
Astragali radix
diabetic neuropathy(DPN)
diabetic cardiomyopathy(DCM)
diabetic nephropathy(DN)
diabetic retinopathy(DR)
diabetic foot
