摘要
目的探讨宫腔镜下中重度宫腔粘连分离术后应用球囊联合防粘连膜(Interceed)预防再次粘连的效果,为临床寻找治疗宫腔粘连的综合方法。方法选择2018年1月至2018年12月在医院妇产科收治的40例经宫腔镜确诊的中重度宫腔粘连患者,40例病人均行宫腔粘连分离术治疗,其中18例术后置入宫内节育器并辅以雌孕激素序贯疗法的患者为对照组,22例术后采用球囊加用防粘连膜置入宫腔,并辅以雌孕激素序贯疗法综合方法的患者为研究组。随访3个月,分别于手术前及术后3个月观察两组月经量恢复情况,术后3个月再次行宫腔镜检查,评估宫腔形态恢复情况,对比两组临床疗效。结果对照组总有效率为72.22%,研究组总有效率为90.91%,研究组高于对照组(P<0.05);研究组宫腔形态、月经恢复情况均优于对照组(P均<0.05)。结论中重度宫腔粘连分离术后放置球囊加用防粘连膜可有效改善月经情况、预防术后再次粘连。
Objective To investigate the effect of hysteroscopic surgery on the prevention of re-adhesion by using balloon combined with sodium hyaluronate in the treatment of moderate to severe intrauterine adhesions and to find a comprehensive method for the treatment of intrauterine adhesions.Methods Forty patients with moderate to severe intrauterine adhesions diagnosed by hysteroscopic surgery were enrolled in the Department of Obstetrics and Gynecology from January 2018 to December 2018.All 40 patients underwent intrauterine adhesions.Eighteen patients were treated with intrauterine adhesions.Patients who entered the intrauterine device and supplemented with estrogen and progesterone sequential therapy were used as the control group,and 22 patients were treated with balloon plus sodium hyaluronate into the uterine cavity,supplemented by a combination of estrogen and progesterone sequential therapy as the research group.After 3 months,the recovery of menstrual volume was observed in the two groups.Hysteroscopy was performed again in March to evaluate the recovery of uterine cavity morphology,and the clinical efficacy of the two groups was compared.Results The total effective rate of the control group was 72.22%,and the total effective rate of the study group was 90.91%.The study group was significantly higher than the control group,the difference was statistically significant(P<0.05).The number of patients with no more adhesions and no change in menstruation was significantly higher than that of the study group.The difference was statistically significant(P all<0.05).Conclusion The combination of balloon and sodium hyaluronate after moderate to severe intrauterine adhesions can effectively improve menstrual conditions and prevent postoperative adhesions without significant adverse effects.
作者
李亚萍
苏萍
李建春
LI Yaping;SU Ping;LI Jianchun(The Fifth People’s Hospital of Ningxia,Shizuishan 753000,China;Fourth People's Hospital of Kunshan of Jiangsu Province,Kunshan 252000,China)
出处
《宁夏医科大学学报》
2021年第3期302-305,共4页
Journal of Ningxia Medical University
关键词
宫腔粘连
球囊
防粘连膜
宫内节育器
intrauterine adhesion
balloon
sodium hyaluronate
intrauterine device
