摘要
不明原因栓塞性卒中(embolic stroke of undetermined source,ESUS)是卒中的一种亚型,约占缺血性卒中30%。房性心肌病是用来描述心房结构、功能和电异常的一种病理生理学概念,目前研究显示房性心肌病患者可能先于心房颤动发生,亦可形成血栓进而引起血栓栓塞,故被认为是ESUS的一种潜在机制。该综述将讨论房性心肌病及ESUS的概念、机制和关联,以及二者与心房颤动之间的转化关系,旨在促进对于房性心肌病与ESUS的概念、病理生理学机制的理解,从而在临床上更好地管理ESUS患者。
Embolic stroke of undetermined source(ESUS),a subtype of stroke,accounts for around 30%of ischemic stroke.Atrial cardiomyopathy is a pathophysiological concept used to describe atrial structure,function and electrical abnormalities.Atrial cardiomyopathy can occur before atrial fibrillation and is also responsible for thrombogenesis and thromboembolism,so it is considered to be a potential mechanism of ESUS.This review aims to discuss the concepts,mechanisms and associations of atrial cardiomyopathy and ESUS,as well as the conversion relationship among the atrial cardiomyopathy and ESUS and atrial fibrillation,to better understand the pathophysiological mechanisms of atrial cardiomyopathy and promote the management of these patients in clinical practices.
作者
宁玉烨
罗国刚
李国良
NING Yu-ye;LUO Guo-gang;LI Guo-liang(Stroke Centre and Department of Neurology,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China;Atrial Fibrillation Centre and Department of Cardiovascular Medicine,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061,China)
出处
《中国心血管病研究》
CAS
2021年第3期284-288,共5页
Chinese Journal of Cardiovascular Research
关键词
房性心肌病
不明原因栓塞性卒中
隐源性卒中
心房颤动
Atrial cardiomyopathy
Embolic stroke of undetermined source
Cryptogenic strokes
Atrial fibrillation
