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超声引导下腰骶神经丛阻滞联合吸入麻醉对老年下肢手术患者认知功能及神经细胞因子水平的影响 被引量:2

Effects of ultrasound-guided lumbosacral plexus block combined with inhalation anesthesia on cognitive function and nerve cell factor levels in elderly patients with lower extremity surgery
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摘要 目的探讨超声引导下腰骶神经丛阻滞(LPB)联合吸入麻醉在老年下肢手术患者中的应用效果。方法选择2019年3月至2020年3月择期行外科手术治疗的88例老年下肢骨折手术患者,按随机数字表法将其分为对照组和观察组,每组44例。对照组采用喉罩吸入麻醉,观察组采用LPB联合吸入麻醉。比较两组麻醉效果。结果观察组拔除喉罩时间、麻醉复苏室滞留时间、呼之睁眼时间、下床活动时间均短于对照组(P<0.05)。T1、T2、T3时,观察组HR、MAP低于对照组(P<0.05)。术后24 h,观察组VAS、MMSE、MoCA评分和S-100β蛋白、NSE水平优于对照组(P<0.05)。结论超声引导下LPB联合吸入麻醉可维持血流动力学稳定,更利于患者术后恢复,减轻对神经细胞的损伤,改善认知功能,安全性高。 Objective To explore the application effect of ultrasound-guided lumbosacral plexus block(LPB)combined with inhalation anesthesia in elderly patients with lower extremity surgery.Methods Eighty-eight elderly patients with lower extremity farcture surgery who underwent elective surgical treatment from March 2019 to March 2020 were selected,and the patients were divided into control group and observation group according to the random number table method,with 44 cases in each group.The control group received laryngeal mask inhalation anesthesia,and the observation group received LPB combined with inhalation anesthesia.The anesthesia effect between the two groups was compared.Results The extubation time of laryngeal mask,the retention time of anesthesia recovery unit,the time of opening eyes upon calling and getting out of bed in the observation group were shorter than those in the control group(P<0.05).At T1,T2 and T3,the HR and MAP of the observation group were lower than those of the control group(P<0.05).At 24 h after operation,the scores of VAS,MMSE and MoCA and the levels of S-100βprotein and NSE of the observation group were better than those of the control group(P<0.05).Conclusion Ultrasound-guided LPB combined with inhalation anesthesia can maintain hemodynamic stability,more conducive to the patients'postoperative recovery,reducing nerve cell damage,improving cognitive function,and has high safety.
作者 葛亚萍 GE Yaping(People's Hospital of Dingbian County,Yulin 718699,China)
机构地区 定边县人民医院
出处 《临床医学研究与实践》 2021年第11期90-92,95,共4页 Clinical Research and Practice
关键词 超声 腰骶神经丛阻滞 吸入麻醉 老年下肢手术 ultrasound lumbosacral plexus block inhalation anesthesia elderly lower extremity surgery
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